Results 31 to 40 of about 953,364 (296)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Reviving the Demographic Study of the Amish

The Journal of Amish and Plain Anabaptist Studies, 2017
The Amish exhibit distinctive demographic patterns, notably high fertility. While scholars have studied Amish population dynamics for more than a half century, recent research in this area is limited.
Corey Colyer, Cory Anderson, Joseph Donnermeyer, Rachel Stein, Samson Wasao   +4 more
doaj  

Nature and the Environment in Amish Life—David McConnell and Marilyn Loveless

The Journal of Amish and Plain Anabaptist Studies, 2020
"In this symposium review, three agricultural and environmental researchers discuss the book Nature and the Environment in Amish Life by David McConnell and Marilyn Loveless, both of the College of Wooster in Wooster, Ohio.
Steven Reschly, Scot Long, Caroline Brock   +2 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Antimicrobial resistance pattern and RAPD profile of Salmonella Ohio isolated from broiler farms in Al-Najaf and Al-Muthana provinces

Kufa Journal for Veterinary Medical Sciences, 2013
The present study aimed to investigate the molecular epidemiology and resistance patterns of S. Ohio isolates. All the Ohio isolates were resistant to more than three of the antibiotics, upto 10 antimicrobial agents.
Abdullah O. Mansour, Salman Aziz Al-Jbouri, Hayder Mansour oooo   +2 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Where have all the arrows gone? A cross-cultural comparison of Lowland Maya and Central Ohio arrow use

Journal of Lithic Studies
Arrow points are an abundant lithic resource, but exactly how abundant? Recent systematic surveys of the Mayan Lowlands and central Ohio permit a new cross-cultural comparison of arrow use, and factors that may lead to their differing accumulations in ...
Eric Olson
doaj   +1 more source

Carbamazepine-Induced Acute Pancreatitis

Pediatric Neurology Briefs, 1993
A 5-year-old mentally retarded child who developed pancreatitis during accidental acute carbamazepine (CBZ) intoxication is reported from the Department of Pediatrics, Ohio State University, Columbus, Ohio.
J Gordon Millichap
doaj   +1 more source