Results 41 to 50 of about 270,996 (264)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

A Unified Model of Oil/Water Two-Phase Flow through the Complex Pipeline

open access: yesGeofluids, 2021
Oil-water two-phase flow through the complex pipeline, consisting of varying pipes and fittings in series or parallel, is commonly encountered in the petroleum industry.
Qingchun Gao, Zhiming Wang, Quanshu Zeng
doaj   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

open access: yesAdvanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

Study on Oil-Water Two-phase Flow in the Invisible Measuring Pipeline of the Horizontal Tri-electrode Capacitive Sensor

open access: yesMeasurement Science Review
Based on the well logging requirements of horizontal stripper wells, the flow characteristics of the oil-water two-phase flow in the invisible horizontal tri-electrode capacitive sensor (HTCS) measurement pipeline are studied.
Li Lei   +4 more
doaj   +1 more source

A Semianalytical Two-Phase Imbibition Model in Dual-Porosity and Dual-Permeability Reservoirs

open access: yesGeofluids, 2021
The pressure transient behavior of water injection well has been extensively investigated under single-phase flow conditions. However, when water is injected into formation, there are saturation gradients within the water flooded area.
Mengmeng Li   +4 more
doaj   +1 more source

Understanding the Stochastic Nature of Process Parameter Development of Blown Powder Laser Beam Directed Energy Deposition Additive Manufacturing of Pure Molybdenum

open access: yesAdvanced Engineering Materials, EarlyView.
Identified through the use of statistical design of experiments and metallographic investigation, this study exposes the stochastic origins of intergranular cracks in blown powder laser beam directed energy deposition additive manufacturing of pure molybdenum. It further demonstrates a successful crack mitigation approach with direct correlation to the
Nathaniel J. Lies   +2 more
wiley   +1 more source

Gamma radiation methods for clamp-on multiphase flow metering [PDF]

open access: yes, 2008
The development of a cost-effective multiphase flow meter to determine the individual phase flow rates of oil, water and gas was investigated through the exploitation of a single clamp-on gamma densitometer and signal processing techniques.
Blaney, S.
core  

Electrified Damage in Motion Systems

open access: yesAdvanced Engineering Materials, EarlyView.
The electrified damage in motion systems is a fundamental framework presenting the degradation pathway arising from the coupling of electrical energy transport with mechanical contact and interfacial chemistry. The framework positions electrified damage as a distinct degradation regime with unique characteristic surface morphologies and failures of ...
M. Humaun Kabir   +2 more
wiley   +1 more source

Experimental Investigation On The Holdup Distribution Of Oil-Water Two-Phase Flow In Horizontal Parallel Tubes

open access: yes, 2008
An experimental investigation was conducted to study the holdup distribution of oil and water two-phase flow in two parallel tubes with unequal tube diameter.
Chang Y(常英)   +4 more
core   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

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