Results 51 to 60 of about 141,115 (293)

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

An end-to-end fault interpretation method driven by visual foundation model with domain adaptation fine-tuning

Scientific Reports
Accurate geological fault interpretation is critical for the safe construction and efficient operation of underground gas storage sites. However, traditional manual interpretation suffers from inefficiency and reliance on expert experience. Existing deep
Yun Liu, Fengyuan Zhang, Huanyu Zou, Famu Huang, Ziheng Zhu, Shijie Zhao, Jinshuo Yan, Sirui Jiang, Jizhou Tang   +8 more
doaj   +1 more source

Оцінка умов руйнування тривалоексплуатованих газопроводів [PDF]

, 2017
For long-term operation of main oil and gas pipeline steels the technique of deterring the critical crack growth resistance of pipeline steels by investigation using experimentally obtained diagram of "force-deflection" samples destruction was suggested.
Грабовський, Р. С., Грицанчук, А. В., Мазур, Мирослав Павлович, Хабінський, В.   +3 more
core  

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Establishment of simulation model and optimization of process operation for verification station of natural gas flowmeter

You-qi chuyun, 2021
With the explosive growth of natural gas consumption, the demand of gas measurement in trade transaction for flowmeter verification is increasing.
Xu HAN, Nan SUN, Xiran ZHANG, Zhe LIU, Kai WEN   +4 more
doaj   +1 more source

Аналіз і модернізація обладнання для експлуатації Гуцулівського газового родовища [PDF]

, 2013
Обгрунтовано необхідність розробки і експлуатації родовищ з невеликими запасами нафти чи газу, а саме Гуцулівського газового родовища, яке розташоване в Косівському районі Івано-Франківської області.
Ващаєв, О. В., Війтенко, В. І., Концур, І. Ф., Лютко, Т. І., Лях, М. М.   +4 more
core  

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science, EarlyView.
ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
wiley   +1 more source

A bridge to a low carbon future? Modelling the long-term global potential of natural gas [PDF]

, 2014
This project uses the global TIMES Integrated Assessment Model in UCL (‘TIAM-UCL’) to provide robust quantitative insights into the future of natural gas in the energy system and in particular whether or not gas has the potential to act as a ‘bridge’ to ...
Anandrajah, Gabrial, Bradshaw, Mike, Ekins, Paul, McGlade, Christophe, Watson, Jim   +4 more
core   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Monitoring of Oil and Gas Pipelines by Use of VTOL-Type Unmanned Aerial Vehicles [PDF]

, 2016
The vast and diverse spread of the oil and gas pipeline infrastructure makes real-time monitoring of the entire network a very costly task. This topology has provided vandals and crude-oil thieves with the opportunity of tapping the pipelines and ...
Idachaba, F.E.
core