Results 31 to 40 of about 14,054 (273)

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Flow Field Analysis of Spur Gear Meshing Period Under the State of Oil-immersion Lubrication

open access: yesJixie chuandong, 2018
In order to make clear the mechanism of oil churning loss of gearbox and to further improve the efficiency of gear transmission,the factors that effects on oil churning losses are studied.
Zhou Yajie, Wang Bin, Ling Jianhui
doaj  

Detailed Investigations on the Oil Flow in Dip-Lubricated Gearboxes by the Finite Volume CFD Method

open access: yesLubricants, 2018
Three main concerns are in the focus of the development of geared transmissions nowadays: load carrying capacity, noise–vibration–harshness (NVH) behavior, and efficiency.
Hua Liu   +3 more
doaj   +1 more source

Assurance of lubricant supply in wet-lubricated space bearings [PDF]

open access: yes, 1976
Conventional lubrication techniques appear to be satisfactory, but rigorous proof of meeting a ten-year life requirement is lacking. One approach provides additional lubricant only when commanded from ground control, while the other passively augments ...
Glassow, F. A.
core   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

open access: yesAdvanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen   +14 more
wiley   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Study on the Thermal Distribution Characteristics of High-Speed and Light-Load Rolling Bearing Considering Skidding

open access: yesApplied Sciences, 2018
Skidding, which frequently occurs in high-speed rolling bearings, has a significant effect on the thermal distribution and service reliability of the bearings. An improved theoretical model of friction power loss distribution in high-speed and light-load
Junning Li, Jiafan Xue, Zhitao Ma
doaj   +1 more source

Model based wind turbine gearbox fault detection on SCADA data [PDF]

open access: yes, 2014
Developing effective wind turbine fault detection algorithm is not only meaningful for improving wind turbine reliability but also crucial for future intelligent wind farm operation and management.
Cao, Mengnan   +6 more
core  

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