Results 41 to 50 of about 14,054 (273)

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Simulation Analysis of Meshing Gear Churning Power Loss based on CFD Method

Jixie chuandong, 2018
It is difficult to determine the gear churning power loss directly by theoretical methods because gear churning power loss has a complex relationship with its influencing factors.
Shen Lin, Ruan Dengfang, Tu Pan
doaj  

Influence of the Lubricant Temperature of Splashed Lubricated Worm Gearbox on Churning Power Losses

ITEGAM-JETIA
The primary goal of lubricating a worm gearbox is to encourage sliding between teeth, which lowers the coefficient of friction and regulates the temperature rise brought on by rolling and sliding friction. Due to both non-load-dependent and load-
Hardik G Chothani, D.J. Marsonia, N.N. Jadeda, S.H. Zala   +3 more
doaj   +1 more source

Experimental and Numerical Investigation of the Outer Ring Cooling Concept in a Hybrid and in an All-Steel Ball Bearing Used in Aero-Engines by the Introduction of a Helical Duct

Aerospace, 2018
Rolling element bearings for aero engine applications have to withstand very challenging operating conditions because of the high thermal impact due to elevated rotational speeds and loads.
Michael Flouros, Peter Gloeckner, Markus Hirschmann, Matthias Martin, Francois Cottier, Dimitra Papailia   +5 more
doaj   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Analytical and Experimental Investigation of Windage–Churning Behavior in Spur, Bevel, and Face Gears

Applied Sciences
This paper presents comparable sets of the no-load power loss as a product of windage and churning behaviors of a family of various rotating parts (i.e., disc, spur gear, straight bevel gear, and orthogonal face gear).
Yu Dai, Caihua Yang, He Liu, Xiang Zhu
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

The phase shift of an ultrasonic pulse at an oil layer and determination of film thickness [PDF]

, 2005
An ultrasonic pulse incident on a lubricating oil film in a machine element will be partially reflected and partially transmitted. The proportion of the wave amplitude reflected, termed the reflection coefficient, depends on the film thickness and the ...
Astridge D. G., B. W. Drinkwater, R. S. Dwyer-Joyce, S Kasolang, T Reddyhoff   +4 more
core   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Numerical Simulation and Experimental Verification of the Two-phase Flow Characteristic of the Automotive Gear

Jixie chuandong, 2019
Aiming at the two-phase flow characteristics of the automotive gear, based on the PLIC-VOF algorithm, the three-dimensional churning process model of the gear is numerically calculated by Matlab software.
Zou Lin Du Mingya Jia Bing Xu Jinli
doaj