Results 41 to 50 of about 8,917 (263)

Influence of bearing capacity of oil tank on evaporation loss of oil products

You-qi chuyun, 2020
If the oil vapor from the tanks is discharged into the atmosphere, the environment pollution will be caused and the human health will be threated. Definitely, pressure and temperature changes are the main factors causing evaporation of oil products in ...
Jie FANG, Weiqiu HUANG, Aihua LYU
doaj   +1 more source

A novel PCOS rat model and an evaluation of its reproductive, metabolic, and behavioral phenotypes

Reproductive Medicine and Biology, 2022
Background Although animal models of PCOS have been used in many studies, none of them can reproduce both the reproductive and metabolic phenotypes of PCOS. In addition, behavioral parameters have not been evaluated in PCOS animal models.
Shuhei Kamada, Yuri Yamamoto, Hidenori Aoki, Kou Tamura, Asuka Takeda, Saki Minato, Rie Masaki, Rie Yanagihara, Noriko Hayashi, Yuya Yano, Junki Imaizumi, Tomohiro Kagawa, Atsuko Yoshida, Takako Kawakita, Minoru Irahara, Takeshi Iwasa   +15 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate

Case Reports in Medicine, 2012
We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle). While considered to have a favourable safety profile, serious complications such as oil embolism and ...
Gregory S. Y. Ong, Colin P. Somerville, Timothy W. Jones, John P. Walsh   +3 more
doaj   +1 more source

An MILP approach for detailed scheduling of oil depots along a multi-product pipeline

Petroleum Science, 2017
Oil depots along products pipelines are important components of the pipeline transportation system and down-stream markets. The operating costs of oil depots account for a large proportion of the total system’s operating costs.
Hao-Ran Zhang, Yong-Tu Liang, Qi Liao, Jing Ma, Xiao-Han Yan   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Investigating the dynamics of passenger rolling stock deterioration [PDF]

Transport, 2008
One of the major economic criteria is associated with the growth of maintenance costs of old rail vehicles. The research aims to determine the ageing criteria of passenger rolling stock, which could take into account fuel, diesel oil and repair costs ...
G. Vaičiūnas, L. P. Lingaitis
doaj   +2 more sources

Lifetime Cancer Risk and Hazard Quotient of BTXs Compounds in Iranian Petrochemical and Petroleum Depot Workers

Iranian Journal of Health, Safety and Environment, 2018
Exposing to the high-level of BTXs concentration can occur in the oil-dependent industries and may cause considerable adverse impacts on the health of employees. The main objective of the present study firstly is determining the exposure of petrochemical
Razzagh Rahimpour, Sajjad Farhadi, Mahdi Jalali   +2 more
doaj