Results 171 to 180 of about 367,691 (306)

Analysis of Elasto-hydrodynamic Lubrication Characteristics of Journal Bearings Under Starved Lubrication

open access: yesJixie chuandong
With the gradual increasing of wind turbine power, the advantages of journal bearings in wind turbine gearboxes are gradually prominent. When the lubrication system is blocked or the oil supply is insufficient, the journal bearing will be in the starved ...
Zhao Dongxu, Ni Yanguang, Ma Zikui
doaj  

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

open access: yesAdvanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo   +6 more
wiley   +1 more source

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang   +11 more
wiley   +1 more source

Research of the Oil film pressure in plain Bearing : The main point of the treatise

open access: yesJournal of the Society of Mechanical Engineers, 1949
Tokio SASAKI   +2 more
openaire   +3 more sources

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

open access: yesAdvanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani   +10 more
wiley   +1 more source

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