Results 21 to 30 of about 43,617 (260)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Morphology Characterization of Micro-clearance Oil Film of Hydrostatic Bearing Under Extreme Conditions

open access: yes工程科学与技术, 2022
Under extreme working conditions, the lubricating oil film in the clearance of hydrostatic bearing is subjected to the combined action of strong extrusion pressure and strong shear force.
Xiaodong YU   +6 more
doaj  

Influence of Surface Texture of Guide Rail on Surface Friction in High Speed Pin Insertion Mechanism [PDF]

open access: yesZhengzhou Daxue xuebao. Gongxue ban
Taking the rail friction pair with surface texture in the pin insertion machine as the research object, the influence of surface texture on its friction performance was studied with the consideration of surface roughness, load fluctuation, speed ...
WANG Xinglong   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Influence of Platen Deformation Compensation on Motion Error of Hydrostatic Guideways

open access: yesIEEE Access
The deformation of a pressure plate induced by oil film pressure is unavoidable in hydrostatic guideways, and the fluid–structure interaction between the oil film and the supporting structure significantly affects motion accuracy.
Zhiwei Wang   +4 more
doaj   +1 more source

Oil Film and Pressure Characteristics of the Friction Pair

open access: yesOALib, 2018
In order to improve the friction performance of the valve plate and improve the oil film bearing capacity of the valve plate, the influence of the fluid-solid coupling on the performance of the oil film of the valve plate was studied. The lubrication characteristics of the surface texture of the valve plate was studied systematically based on the ...
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

INFLUENCE OF LOAD AND SPEED CHANGE ON LUBRICATION PERFORMANCE OF LOW SPEED HEAVY DUTY BEARINGS

open access: yesJixie qiangdu, 2019
In order to study the lubricating property of low-speed heavy-duty bearing under the condition of different loads and speed, such as the oil film thickness, oil film pressure and changes of oil film velocity. Building model of fluid-structure interaction
ZHAO LiJuan, SHI BaiSheng, ZHANG MeiChen
doaj  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

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