Results 81 to 90 of about 212,363 (310)

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

open access: yesAdvanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey   +6 more
wiley   +1 more source

Keystone XL Pipeline: Overview and Recent Developments [PDF]

open access: yes, 2015
[Excerpt] This report describes the Keystone XL Pipeline Project and the process that the State Department must complete to decide whether it will approve or deny TransCanada’s permit application.
Fergusson, Ian F   +6 more
core   +4 more sources

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

open access: yesAdvanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu   +8 more
wiley   +1 more source

Optimal valve location in long oil pipelines [PDF]

open access: yes
We address the valve location problem, one of the basic problems in design of long oil pipelines. Whenever a pipeline is depressurized, the shutoff valves block the oil flow and seal the damaged part of the pipeline.
Grigoriev, A., Grigorieva, N.V.
core   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

open access: yesAdvanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu   +5 more
wiley   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

The role of Turkey in the European energy market [PDF]

open access: yes, 2012
The essay in this Med-Agenda aims to examine the role of Turkey in the global energy market within the context of European Energy Security. In the essay we have attempted to answer the following questions: What will the future role of Turkey be in the ...
Yılmaz, Bahri, Yilmaz, Bahri
core  

Breach of faith? Italian-Soviet Cold War trading and Eni’s international oil scandal [PDF]

open access: yes, 2015
The article was submitted on 10.07.2015.By the late-1950s, Soviet oil exports to Western Europe caused widespread concern in a number of Western countries as these feared that Moscow could use oil to weaken their economic interests.
Cantoni, R., Кантони, Р.
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

New England Overview: A Guide to Large-Scale Energy Infrastructure Issues in 2015 [PDF]

open access: yes, 2015
The report outlines how regional electricity and natural gas infrastructure decisions are made. It examines the current proposals to expand electricity transmission lines and natural gas pipelines into New England, as solutions to electricity and gas ...
Jonathan Raab, Paul Peterson
core  

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