Results 221 to 230 of about 131,193 (312)

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard   +10 more
wiley   +1 more source

The evidence-based indications of 0.1% topical tacrolimus in ophthalmology: a scoping review. [PDF]

open access: yesTher Adv Ophthalmol
Lam PD   +5 more
europepmc   +1 more source

Transness is our salve: How trans identity facilitates healing from relational trauma with parental figures

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract Transgender and nonbinary (TNB) individuals experience high rates of relational trauma from parental figures, yet their pathways to healing remain underexplored. This qualitative study used constructivist grounded theory to develop a theoretical framework of how TNB adults heal from parental relational trauma.
Joonwoo Lee   +4 more
wiley   +1 more source

Clinically Meaningful Improvements in Quality of Life, Including Sleep, With Two‐Week and Monthly Dosed Rademikibart: A Phase 2 Randomized Trial in Adults With Moderate‐to‐Severe Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
Rademikibart, a potent IL‐4Rα‐targeting antibody, achieved its primary endpoint as a treatment for adults with moderate‐to‐severe atopic dermatitis (AD) in the CBP‐201‐WW001 Phase 2 trial. There is a need for AD treatment options with convenient dosing intervals.
Jonathan I. Silverberg   +2 more
wiley   +1 more source

First Report of Homozygous COL7A1 c.5756delG Mutation Causing Recessive Dystrophic Epidermolysis Bullosa in a Non‐Consanguineous Japanese Family

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Severe recessive dystrophic epidermolysis bullosa (RDEB) is usually caused by biallelic loss‐of‐function mutations in COL7A1. While the c.5756delG variant has been previously reported in heterozygous form, its clinical impact in homozygosity has not been described.
Nozomi Kohama   +6 more
wiley   +1 more source

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