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American Journal of Psychiatry, 2020
OBJECTIVE A combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment is intended to provide the efficacy of olanzapine
Christoph U Correll +2 more
exaly +2 more sources
OBJECTIVE A combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment is intended to provide the efficacy of olanzapine
Christoph U Correll +2 more
exaly +2 more sources
Olanzapine is a thienobenzodiazepine that blocks especially the serontonin (5-hydroxytryptamine [5-HT]) 5-HT2A and the dopamine D2 receptors as well as muscarinic (M1), histamine (H1), 5-HT2C, 5-HT3 to 5-HT6, adrenergic (α l ), and D4 receptors.
Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü +2 more
openaire +3 more sources

