Bioorthogonal CRISPR/Cas9-Drug Conjugate: A Combinatorial Nanomedicine Platform. [PDF]
Adv Sci (Weinh), 2023 Here, a nanomedicine platform based on bioorthogonal CRISPR/Cas9‐drug conjugates, which can be self‐delivered in vivo and exert strong anti‐tumor effects upon gene editing and chemotherapy is developed. The current development provides a powerful strategy that can be widely applied for the therapy of human diseases such as cancer and genetic disorders.
Beha MJ +9 more
europepmc +2 more sources
PEMBUATAN APLIKASI OLAP UNTUK ANALISIS STUDI KELAYAKAN PROYEK: STUDI KASUS PEMERINTAH KABUPATEN KEDIRI [PDF]
JUTI: Jurnal Ilmiah Teknologi Informasi, 2003 Untuk memperbaiki kinerja pemerintah, maka kelembagaan negara, instansi pemerintah, entitas ekonomi, dan satuan kerja sektor publik harus dikelola dengan konsep good governance.
Joko Lianto, Ruly Damaratri
doaj +5 more sources
Advanced visualization for OLAP [PDF]
Proceedings of the 6th ACM international workshop on Data warehousing and OLAP - DOLAP '03, 2003 Data visualization is one of the big issues of database research. OLAP as a decision support technology is highly related to the developments of data visualization area. In this paper we demonstrate how the Cube Presentation Model (CPM), a novel presentational model for OLAP screens, can be naturally mapped on the Table Lens, which is an advanced ...
Andreas Maniatis +3 more
openalex +3 more sources
Unmatched Cell Line Collections Are Not Optimal for Identification of PARP Inhibitor Response and Drug Synergies. [PDF]
J Cell Mol MedABSTRACT PARP inhibitors show great efficacy in BRCA1/2‐mutated patients, but many preclinical studies, including combination therapies, fail to translate clinically, likely due to the limitations of preclinical models. This brief report aimed to identify appropriate cell line models to investigate PARP inhibitor sensitivity and synergies. An in silico
Phan Z, Fernandez KJ, Caldon CE.
europepmc +2 more sources
Artificial intelligence-assisted ultrasound-guided regional anaesthesia: An explorative scoping review. [PDF]
J Exp OrthopAbstract Purpose The present study reviews the available scientific literature on artificial intelligence (AI)‐assisted ultrasound‐guided regional anaesthesia (UGRA) and evaluates the reported intraprocedural parameters and postprocedural outcomes.
Marino M +7 more
europepmc +2 more sources
High-Fidelity Aerothermal Engineering Analysis for Planetary Probes Using DOTNET Framework and OLAP Cubes Database [PDF]
International Journal of Aerospace Engineering, 2009 This publication presents the architecture integration and implementation of various modules in Sparta framework. Sparta is a trajectory engine that is hooked to an Online Analytical Processing (OLAP) database for Multi-dimensional analysis capability ...
Prabhakar Subrahmanyam
doaj +2 more sources
Evaluation of SOVAT: An OLAP-GIS decision support system for community health assessment data analysis [PDF]
BMC Medical Informatics and Decision Making, 2008 Background Data analysis in community health assessment (CHA) involves the collection, integration, and analysis of large numerical and spatial data sets in order to identify health priorities.
Parmanto Bambang +2 more
doaj +2 more sources
n-Dimensional intuitionistic fuzzy index matrix representation of multidimensional data partitioning methods [PDF]
Notes on IFS, 2023 In the present research paper, the data partitioning operations are investigated. Their functionalities are discussed. n-dimensional intuitionistic fuzzy index matrix is used to represent the multidimensional data partitioning.
Veselina Bureva, Krassimir T. Atanassov
doaj +1 more source
Pervasive Real-Time Analytical Framework—A Case Study on Car Parking Monitoring
Information, 2023 Due to the amount of data emerging, it is necessary to use an online analytical processing (OLAP) framework capable of responding to the needs of industries.
Francisca Barros +3 more
doaj +1 more source
Prognostic risk estimates of patients with multiple sclerosis and their physicians: comparison to an online analytical risk counseling tool. [PDF]
PLoS ONE, 2013 BACKGROUND: Prognostic counseling in multiple sclerosis (MS) is difficult because of the high variability of disease progression. Simultaneously, patients and physicians are increasingly confronted with making treatment decisions at an early stage, which
Christoph Heesen +8 more
doaj +1 more source