Results 11 to 20 of about 9,065 (221)
VEGF inhibitor-induced vascular dysfunction involves redox-sensitive PARP activation and SIRT1 disruption. [PDF]
Exp PhysiolAbstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Neves KB +3 more
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A Tale of Two Cell Lines: Characterization of Differential Efficacy of Small Molecule Drugs Cediranib and NU-7441 on Primary Versus Metastatic Colorectal Cancer. [PDF]
Pharmacol Res PerspectABSTRACT Colorectal cancer is recognized as one of the leading causes of cancer death amongst both sexes in the U.S. Despite rigorous screening, those diagnosed with colon cancer often face poor prognosis, and approximately 70% of affected patients will develop metastatic relapse. The investigation of colon carcinoma cell lines' genetic variability and
Tsang JD, Roberts CM.
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Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer. [PDF]
Mol OncolScreening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Yusoh NA +5 more
europepmc +2 more sources
Intelligent Data Analysis, 2017 Online Analytical Processing (OLAP) comprises tools and algorithms that allow querying multidimensional databases. It is based on the multidimensional model, where data can be seen as a cube, where each cell contains one or more measures can be aggregated along dimensions.
Bart Kuijpers, Alejandro A. Vaisman
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Journal of Advances in Information Technology, 2010 OLAP performance and its data visualization can be improved using different types of enhancement techniques. Previous research has taken two separate directions in OLAP performance improvement and visualization enhancement respectively. Some recent works
Muhammad Usman +2 more
doaj +1 more source
Research and implementation of HTAP for distributed database
Xibei Gongye Daxue Xuebao, 2021 Data processing can be roughly divided into two categories, online transaction processing OLTP(on-line transaction processing) and online analytical processing OLAP(on-line analytical processing).
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Proceedings of the 13th International Conference on Extending Database Technology, 2010 So far, data warehousing has often been discussed in the light of complex OLAP queries and as reporting facility for operative data. We argue that business planning as a means to generate plan data is an equally important cornerstone of a data warehouse system, and we propose it to be a first-class citizen within an OLAP engine.
Bernhard Jaecksch +2 more
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Querying data warehouses efficiently using the Bitmap Join Index OLAP Tool
CLEI Electronic Journal, 2012 Data warehouse and OLAP are core aspects of business intelligence environments, since the former store integrated and time-variant data, while the latter enables multidimensional queries, visualization and analysis.
Anderson Chaves Carniel +1 more
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MULTIDIMENSIONAL DATABASES IN INFORMATION SYSTEMS OF UNIVERSITIES [PDF]
Scientific Journal of Astana IT University, 2022 The article is devoted to the description of the method of multidimensional database, which is an effective method of data storage, which allows analyzing data qualitatively, and most importantly in a short time.
A. Mukasheva, D. Yedilkhan, M. Aldiyar
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The Use of Column-Based DBMSS to Form Multidimensional Data Structures
Современные информационные технологии и IT-образование, 2023 The work is devoted to the analysis of the method of designing information systems using the “Data vault” modeling technology. The described approach can be used when building a data warehouse within a multidimensional information system based on the ...
Dmitry Kunitsky, Maxim Fomin
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