Safety, Efficacy, and Patient‐Reported Outcomes From a Phase 2 Randomized Trial of Pozelimab and Cemdisiran Combination in Patients With Paroxysmal Nocturnal Hemoglobinuria [PDF]
eJHaemIntroduction Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra‐rare, life‐threatening disease associated with chronic intravascular hemolysis due to uncontrolled complement activation.
Jun‐Ho Jang +12 more
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Long-term efficacy and safety of erenumab in Japanese patients with episodic and chronic migraine: results from a 28-week open-label treatment period of a randomised trial [PDF]
BMJ Open, 2023 Objectives To evaluate the 1-year efficacy and safety of once-monthly erenumab 70 mg following a 24-week double-blind treatment period (DBTP) of a phase III randomised study of Japanese patients with episodic migraine (EM) or chronic migraine (CM).Design
Koichi Hirata +9 more
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Long-term safety and continued clinical benefit of erenumab 70 mg in Asian patients with chronic migraine: an open-label extension of the phase 3 DRAGON study [PDF]
The Journal of Headache and PainBackground Erenumab is a fully human monoclonal antibody targeting the calcitonin gene-related peptide receptor. Several double‐blind studies have demonstrated the clinical benefits of erenumab in migraine prevention. However, long-term studies on safety
Shengyuan Yu +9 more
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Arthroscopic Bone Marrow Stimulation or Non-Operative Treatment for Osteochondral Lesions of the Tibial Plafond [PDF]
Foot & Ankle Orthopaedics, 2022 Category: Ankle; Arthroscopy Introduction/Purpose: A paucity of clinical results from osteochondral lesion of the tibial plafond (OLTP) treatment exists in the literature.
Quinten Rikken +3 more
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Osteotomy and Filling for Osteochondral Lesions of the Tibial Plafond: A Novel Morphology Based Surgical Technique [PDF]
Foot & Ankle OrthopaedicsCategory: Ankle Introduction/Purpose: Symptomatic primary (large) cystic and non-primary osteochondral lesions of the medial and central tibial plafond are challenging entities to treat. These lesions may benefit from a lesion specific treatment approach.
Quinten Rikken MD +4 more
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Osteochondral Lesions of the Tibial Plafond: A Restorative Procedure for Cystic Defects [PDF]
Video Journal of Sports MedicineBackground: Osteochondral lesions of the tibia plafond (OLTPs) are an uncommon problem that can generate pain. Indications: Arthroscopic techniques can provide symptomatic relief and improved outcomes when conservative management has failed.
Francis Bustos MD, Richard Ferkel MD
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MULTIDIMENSIONAL DATABASES IN INFORMATION SYSTEMS OF UNIVERSITIES [PDF]
Scientific Journal of Astana IT University, 2022 The article is devoted to the description of the method of multidimensional database, which is an effective method of data storage, which allows analyzing data qualitatively, and most importantly in a short time.
A. Mukasheva, D. Yedilkhan, M. Aldiyar
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Applied Sciences, 2021 Electronic medical record (EMR) data vary between institutions. These data should be converted into a common data model (CDM) for multi-institutional joint research. To build the CDM, it is essential to integrate the EMR data of each hospital and load it
Tong Min Kim +5 more
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Research and implementation of HTAP for distributed database
Xibei Gongye Daxue Xuebao, 2021 Data processing can be roughly divided into two categories, online transaction processing OLTP(on-line transaction processing) and online analytical processing OLAP(on-line analytical processing).
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Health-care databases and its role in transformation of medicine
Journal of the Scientific Society, 2020 Health-care database is a collection of health-care data organized for storage, accessibility, and retrieval. Health-care database serves to replace the paper documents, filing cabinets of old, and file folders, which will be more convenient and ...
Lakshmi Venkata Simhachalam Kutikuppala +4 more
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