Safety, Efficacy, and Patient‐Reported Outcomes From a Phase 2 Randomized Trial of Pozelimab and Cemdisiran Combination in Patients With Paroxysmal Nocturnal Hemoglobinuria [PDF]
eJHaemIntroduction Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra‐rare, life‐threatening disease associated with chronic intravascular hemolysis due to uncontrolled complement activation.
Jun‐Ho Jang +12 more
doaj +3 more sources
Thespis: Causally-consistent OLTP [PDF]
Annals of computer science and information systems, 2021 Data Consistency defines the validity of a data set according to some set of rules, and different levels of data consistency have been proposed. Causal consistency is the strongest type of consistency possible when data is stored in multiple locations, and fault tolerance is desired.
Carl Camilleri +2 more
doaj +3 more sources
Long-term efficacy and safety of erenumab in Japanese patients with episodic and chronic migraine: results from a 28-week open-label treatment period of a randomised trial [PDF]
BMJ Open, 2023 Objectives To evaluate the 1-year efficacy and safety of once-monthly erenumab 70 mg following a 24-week double-blind treatment period (DBTP) of a phase III randomised study of Japanese patients with episodic migraine (EM) or chronic migraine (CM).Design
Koichi Hirata +9 more
doaj +2 more sources
OLTP on hardware islands [PDF]
Proceedings of the VLDB Endowment, 2012 Modern hardware is abundantly parallel and increasingly heterogeneous. The numerous processing cores have nonuniform access latencies to the main memory and to the processor caches, which causes variability in the communication costs. Unfortunately, database systems mostly assume that all processing cores are the same and that microarchitecture ...
Danica Porobic +4 more
core +6 more sources
Arthroscopic Bone Marrow Stimulation or Non-Operative Treatment for Osteochondral Lesions of the Tibial Plafond [PDF]
Foot & Ankle Orthopaedics, 2022 Category: Ankle; Arthroscopy Introduction/Purpose: A paucity of clinical results from osteochondral lesion of the tibial plafond (OLTP) treatment exists in the literature.
Quinten Rikken +3 more
doaj +2 more sources
Osteotomy and Filling for Osteochondral Lesions of the Tibial Plafond: A Novel Morphology Based Surgical Technique [PDF]
Foot & Ankle OrthopaedicsCategory: Ankle Introduction/Purpose: Symptomatic primary (large) cystic and non-primary osteochondral lesions of the medial and central tibial plafond are challenging entities to treat. These lesions may benefit from a lesion specific treatment approach.
Quinten Rikken MD +4 more
doaj +2 more sources
Osteochondral Lesions of the Tibial Plafond: A Restorative Procedure for Cystic Defects [PDF]
Video Journal of Sports MedicineBackground: Osteochondral lesions of the tibia plafond (OLTPs) are an uncommon problem that can generate pain. Indications: Arthroscopic techniques can provide symptomatic relief and improved outcomes when conservative management has failed.
Francis Bustos MD, Richard Ferkel MD
doaj +2 more sources
Oltp in the cloud: architectures, tradeoffs, and cost
VLDB JournalAbstract What is the best architecture for cloud OLTP systems? How costly is it to run a specific workload? Which and how many hardware instances should be provisioned? To answer such questions systematically, we develop an analytical model framework for cloud OLTP.
Michael Haubenschild
exaly +2 more sources
MULTIDIMENSIONAL DATABASES IN INFORMATION SYSTEMS OF UNIVERSITIES [PDF]
Scientific Journal of Astana IT University, 2022 The article is devoted to the description of the method of multidimensional database, which is an effective method of data storage, which allows analyzing data qualitatively, and most importantly in a short time.
A. Mukasheva, D. Yedilkhan, M. Aldiyar
doaj +1 more source
Applied Sciences, 2021 Electronic medical record (EMR) data vary between institutions. These data should be converted into a common data model (CDM) for multi-institutional joint research. To build the CDM, it is essential to integrate the EMR data of each hospital and load it
Tong Min Kim +5 more
doaj +1 more source