Results 21 to 30 of about 8,156 (191)

P797: A PHASE 2, OPEN-LABEL STUDY EVALUATING THE SAFETY AND EFFICACY OF COMBINATION POZELIMAB AND CEMDISIRAN THERAPY IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA WHO SWITCH FROM ECULIZUMAB [PDF]

Hemasphere, 2023
HemaSphere, Volume 7, Issue S3, August 2023.
Kelly R, Houghton N, Munir T, Muus P, Youngs N, Aurand L, Senk B, Pavani R, Perlee L, Souttou A, Griffin M.   +10 more
europepmc   +2 more sources

MULTIDIMENSIONAL DATABASES IN INFORMATION SYSTEMS OF UNIVERSITIES [PDF]

Scientific Journal of Astana IT University, 2022
The article is devoted to the description of the method of multidimensional database, which is an effective method of data storage, which allows analyzing data qualitatively, and most importantly in a short time.
A. Mukasheva, D. Yedilkhan, M. Aldiyar
doaj   +1 more source

Establishment of the Optimal Common Data Model Environment for EMR Data Considering the Computing Resources of Medical Institutions

Applied Sciences, 2021
Electronic medical record (EMR) data vary between institutions. These data should be converted into a common data model (CDM) for multi-institutional joint research. To build the CDM, it is essential to integrate the EMR data of each hospital and load it
Tong Min Kim, Taehoon Ko, Yoon-sik Yang, Sang Jun Park, In-Young Choi, Dong-Jin Chang   +5 more
doaj   +1 more source

Research and implementation of HTAP for distributed database

Xibei Gongye Daxue Xuebao, 2021
Data processing can be roughly divided into two categories, online transaction processing OLTP(on-line transaction processing) and online analytical processing OLAP(on-line analytical processing).

doaj   +1 more source

Evaluation of vascular risk in patients with migraine with and without aura treated with erenumab: Post hoc analysis of pooled long‐term clinical trial data

Headache: The Journal of Head and Face Pain, Volume 63, Issue 3, Page 418-428, March 2023., 2023
Abstract Objective To assess cardiovascular (CV) safety of erenumab in clinical trial patients associated with degree of CV risk. Background Hypertension has been considered a theoretical risk associated with the inhibition of the calcitonin gene‐related peptide pathway in migraine management, particularly in a patient population with pre‐existing CV ...
David Kudrow, Rima Dafer, David W. Dodick, Amaal Starling, Jessica Ailani, Carrie Dougherty, Kavita Kalidas, Feng Zhang, Rohini Jeswani, Nishil Patel, Ani C. Khodavirdi   +10 more
wiley   +1 more source

Post hoc analysis of clinical trial data and pharmacokinetic data to assess wearing‐off of erenumab within monthly treatment cycle

Headache: The Journal of Head and Face Pain, Volume 63, Issue 2, Page 233-242, February 2023., 2023
Abstract Background Treatment wearing‐off has been reported for calcitonin gene‐related peptide‐pathway monoclonal antibodies, including erenumab, specifically in the last week of the monthly dosing cycle. Objective We sought to determine the consistency of erenumab effect throughout the monthly treatment cycle.
David W. Dodick, Andrew M. Blumenfeld, Rashmi B. Halker Singh, Rachel Williams, Feng Zhang, Po‐Wei Chen, Cheng‐Pang Hsu, Cheng Peng, Josefin Snellman, Mahan Chehrenama, Jessica Ailani   +10 more
wiley   +1 more source

Workload‐Aware Performance Tuning for Multimodel Databases Based on Deep Reinforcement Learning

International Journal of Intelligent Systems, Volume 2023, Issue 1, 2023., 2023
Currently, multimodel databases are widely used in modern applications, but the default configuration often fails to achieve the best performance. How to efficiently manage and tune the performance of multimodel databases is still a problem. Therefore, in this study, we present a configuration parameter tuning tool MMDTune+ for ArangoDB.
Jun Sun, Feng Ye, Nadia Nedjah, Ming Zhang, Dong Xu, Yu-an Tan   +5 more
wiley   +1 more source

Erenumab dosage for migraine prevention: An evidence‐based narrative review with recommendations

Headache: The Journal of Head and Face Pain, Volume 62, Issue 4, Page 420-435, April 2022., 2022
Abstract Background Therapeutic monoclonal antibodies against the calcitonin gene‐related peptide (CGRP) receptor or its ligand have changed the landscape of treatment options for migraine. Erenumab is the first and only fully human monoclonal antibody designed to target and block the CGRP receptor.
Stewart J. Tepper, Huma U. Sheikh, Carrie O. Dougherty, Stephanie J. Nahas, Paul K. Winner, Ananda Krishna Karanam, Andrew M. Blumenfeld, Ahmad Abdrabboh, Soeren Rasmussen, Jamie L. Weiss, Jessica Ailani   +10 more
wiley   +1 more source

[Retracted] Design and Application of Intelligent Management Platform Based on Big Data

Security and Communication Networks, Volume 2022, Issue 1, 2022., 2022
Big data technology has greatly promoted the construction of intelligent administrative management and improved the decision‐making ability continuously. Data mining also lays a solid foundation for the construction of administrative management platform and reflects the potential value of data. In this study, an intelligent management platform based on
Yunuo Su, Minhui Dai, Haoyu Zhou, Hangjun Che   +3 more
wiley   +1 more source

Corpus‐Based Japanese Reading Teaching Database Cloud Service Model

Mathematical Problems in Engineering, Volume 2022, Issue 1, 2022., 2022
With the widespread application of mobile Internet technology, big data, and artificial intelligence, the demand for computing resources in the whole society is growing rapidly. Database cloud service is an online managed high‐availability database service built on a cloud computing platform.
Xiaoying Liu, Naeem Jan
wiley   +1 more source