Results 21 to 30 of about 1,318 (208)

Evaluation of vascular risk in patients with migraine with and without aura treated with erenumab: Post hoc analysis of pooled long‐term clinical trial data

Headache: The Journal of Head and Face Pain, Volume 63, Issue 3, Page 418-428, March 2023., 2023
Abstract Objective To assess cardiovascular (CV) safety of erenumab in clinical trial patients associated with degree of CV risk. Background Hypertension has been considered a theoretical risk associated with the inhibition of the calcitonin gene‐related peptide pathway in migraine management, particularly in a patient population with pre‐existing CV ...
David Kudrow, Rima Dafer, David W. Dodick, Amaal Starling, Jessica Ailani, Carrie Dougherty, Kavita Kalidas, Feng Zhang, Rohini Jeswani, Nishil Patel, Ani C. Khodavirdi   +10 more
wiley   +1 more source

Post hoc analysis of clinical trial data and pharmacokinetic data to assess wearing‐off of erenumab within monthly treatment cycle

Headache: The Journal of Head and Face Pain, Volume 63, Issue 2, Page 233-242, February 2023., 2023
Abstract Background Treatment wearing‐off has been reported for calcitonin gene‐related peptide‐pathway monoclonal antibodies, including erenumab, specifically in the last week of the monthly dosing cycle. Objective We sought to determine the consistency of erenumab effect throughout the monthly treatment cycle.
David W. Dodick, Andrew M. Blumenfeld, Rashmi B. Halker Singh, Rachel Williams, Feng Zhang, Po‐Wei Chen, Cheng‐Pang Hsu, Cheng Peng, Josefin Snellman, Mahan Chehrenama, Jessica Ailani   +10 more
wiley   +1 more source

Proposed framework for enhancing integrity technique using distributed query operation [PDF]

BIO Web of Conferences
Database growth and Storage problems are main concern for large and small enterprises nowadays, which significantly influences the efficiency of database applications. Database archiving is one of the solutions available for management.
Farooq Khattak Umar, Alı Aıtızaz, Hussein, Hussein Al Naffakh Ali   +3 more
doaj   +1 more source

Workload‐Aware Performance Tuning for Multimodel Databases Based on Deep Reinforcement Learning

International Journal of Intelligent Systems, Volume 2023, Issue 1, 2023., 2023
Currently, multimodel databases are widely used in modern applications, but the default configuration often fails to achieve the best performance. How to efficiently manage and tune the performance of multimodel databases is still a problem. Therefore, in this study, we present a configuration parameter tuning tool MMDTune+ for ArangoDB.
Jun Sun, Feng Ye, Nadia Nedjah, Ming Zhang, Dong Xu, Yu-an Tan   +5 more
wiley   +1 more source

Erenumab dosage for migraine prevention: An evidence‐based narrative review with recommendations

Headache: The Journal of Head and Face Pain, Volume 62, Issue 4, Page 420-435, April 2022., 2022
Abstract Background Therapeutic monoclonal antibodies against the calcitonin gene‐related peptide (CGRP) receptor or its ligand have changed the landscape of treatment options for migraine. Erenumab is the first and only fully human monoclonal antibody designed to target and block the CGRP receptor.
Stewart J. Tepper, Huma U. Sheikh, Carrie O. Dougherty, Stephanie J. Nahas, Paul K. Winner, Ananda Krishna Karanam, Andrew M. Blumenfeld, Ahmad Abdrabboh, Soeren Rasmussen, Jamie L. Weiss, Jessica Ailani   +10 more
wiley   +1 more source

[Retracted] Design and Application of Intelligent Management Platform Based on Big Data

Security and Communication Networks, Volume 2022, Issue 1, 2022., 2022
Big data technology has greatly promoted the construction of intelligent administrative management and improved the decision‐making ability continuously. Data mining also lays a solid foundation for the construction of administrative management platform and reflects the potential value of data. In this study, an intelligent management platform based on
Yunuo Su, Minhui Dai, Haoyu Zhou, Hangjun Che   +3 more
wiley   +1 more source

Merging Queries in OLTP Workloads

, 2023
OLTP applications are usually executed by a high number of clients in parallel and are typically faced with high throughput demand as well as a constraint latency requirement for individual statements.
Rehrmann, Robin
core   +2 more sources

Development of Data Warehouse for Financial Report in Faculty of Science, Naresuan University

วารสารวิทยาการสารสนเทศและเทคโนโลยีประยุกต์, 2022
Data warehouse technology is useful for managing large data. The purpose of them are analyzing organization’s datasets to formulate a strategy and direction of the organization. In this paper have present method of the development of data warehouse based
Kittipong Songsiri, Kreangsak Tamee
doaj   +1 more source

Towards Scalable OLTP Over Fast Networks [PDF]

, 2023
Online Transaction Processing (OLTP) underpins real-time data processing in many mission-critical applications, from banking to e-commerce. These applications typically issue short-duration, latency-sensitive transactions that demand immediate ...
Ziegler, Tobias
core   +1 more source

Сравнительный анализ OLAP и OLTP--систем [PDF]

, 2022
В данной статье рассматриваются понятия OLTP и OLAP-систем, приведена сравнительная характеристика данных ...
Сёмина, А. В.
core