Results 171 to 180 of about 62,858 (261)

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

Data, not documents: Moving beyond theories of information‐seeking behavior to advance data discovery

open access: yesJournal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 649-664, April 2025.
Abstract Many theories of human information behavior (HIB) assume that information objects are in text document format. This paper argues four important HIB theories are insufficient for describing users' search strategies for data because of assumptions about the attributes of objects that users seek.
Anthony J. Million   +3 more
wiley   +1 more source

The Tendon‐to‐Bone Seam: A Transtendinous Approach to Rotator Cuff Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract This technique article describes the tendon‐to‐bone seam technique, a knotless, transtendinous approach to arthroscopic rotator cuff repair. The technique employs a single‐use deployment device preloaded with multiple PEEK anchors interconnected with a single polyethylene #2 suture, enabling the surgeon to create a continuous “seam” of ...
James Tyler Frix   +4 more
wiley   +1 more source

Dataset on stand structure in hemiboreal forests across management histories and stand ages. [PDF]

open access: yesData Brief
Rosenvald R   +8 more
europepmc   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari   +6 more
wiley   +1 more source

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