Results 31 to 40 of about 955,969 (257)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Envelhecimento do corpo: noções díspares nas mídias atuais

open access: yesComunicação e Sociedade, 2012
The human being develops through stages which follow the cycle of life, the last of them is old age. Throughout human history aging was understood in different ways according to the society and time.
Sonia Farber
doaj   +1 more source

Preschool anxiety disorders predict different patterns of amygdala-prefrontal connectivity at school-age. [PDF]

open access: yesPLoS ONE, 2015
OBJECTIVE:In this prospective, longitudinal study of young children, we examined whether a history of preschool generalized anxiety, separation anxiety, and/or social phobia is associated with amygdala-prefrontal dysregulation at school-age.
Kimberly L H Carpenter   +7 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Assessment of Enuresis in Children in Erbil City

open access: yesKufa Journal for Nursing Sciences, 2014
Background: Nocturnal enuresis has been observed that bedwetting often occurred in several members of the same family. A study shows that 70% of children who have enuresis have a parent who has a history of the disorder.
Dlair A. K. Chalab   +1 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Correlation between Blood Pressure Levels and Clinical Signs and Symptoms of Hypertensive Patients: A Gender and Age Based Comparison

open access: yesAnnals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, 2018
Objective: To determine correlation between  systolic  and  diastolic  blood  pressure  levels  and  selected signs and symptoms among different gender and age groups of hypertensive patients.
Nargis Anjum   +5 more
doaj   +1 more source

Homeownership in Old Age at the Crossroad Between Personal and National Histories [PDF]

open access: yes, 2011
Compared to other forms of savings for old age, homeownership offers some advantages. Purchasing a home is similar to purchasing an annuity that would insure housing consumption. Moreover, the home may be seen as a secure asset in case of need and perceived as a substitute for the purchase of long term care insurance. It is also a family asset that may
ANGELINI V   +2 more
openaire   +4 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2018
Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016∼2017 in Korea.
Young-Jae Hwang   +18 more
doaj   +1 more source

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