Results 91 to 100 of about 3,988,688 (305)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
, 2014 La session MAPS 7 aura lieu en 2014 à Seignosse, dans les Landes, du dimanche 29 juin au soir au vendredi 4 juillet midi). L'objet de cette édition est de proposer aux membres "fidèles" de MAPS un atelier de réflexion sur les échelles de la modélisation.
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FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Recueil des fiches pédagogiques MAPS en PDF
, 2014 Vous pouvez télécharger le PDF contenant l'intégralité des fiches pédagogiques MAPS sur la page des productions MAPS Vous trouverez également ce recueil de fiches pédagogiques des éditions de MAPS de 2009 à 2013 sur le site HAL : https://hal.archives ...
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
"Ecole thématique" CNRS MAPS 8
, 2014 Le collectif MAPS est heureux d'annoncer que le CNRS a accordé son soutien financier et scientifique à MAPS 8 qui se tiendra donc bien du 21 au 26 Juin 2015 à la Colle sur Loup.
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Usage of the Atlas of Silesia from 1752 in European cartographic publications
Polish Cartographical Review, 2018 The author discusses adaptations of maps from the Atlas of Silesia published by European cartographers in more important atlases and multi-sheet maps from the second half of the 18th and early 19th century.
Wytyczak Roman
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source