Results 111 to 120 of about 589,410 (296)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Historical Maps of the Survey of India (1700-1900)
, 2020 A collection of some 1400 antique manuscript maps out of the 7,949 maps catalogued by the National Archives of India in 1975. These maps and many more, remnants of the early days of mapping in India, were stacked in large piles gathering dust at the ...
Prasad, S.N.
core +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Development of Serbian cartography from the end of XVIII to the beginning of the XX century [PDF]
Zbornik Radova: Geografski Fakultet Univerziteta u Beogradu, 2019 This paper represents summary of development of geographical and cartographical knowledge of Serbian authors about Serbia and Balkan. Important maps in the Serbian language are presented with a brief overview of their content, context and methodology ...
Grčić Mirko
doaj
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
, 2019 A set of about 250 maps of Burma produced by the Survey of India before and during the Second World War at a scale of 1 inch per mile (63,360). Many of these maps are military reprints of earlier maps produced before the war.
Brown, John, Brown, John (8056802)
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Old D-day maps [cartographic material].
, 2004 1841516538 (St Pierre du Mont) (ISBN). 9781841516530 (St Pierre du Mont) (ISBN). 1841516252 (Ouistreham) (ISBN). 9781841516257 (Ouistreham) (ISBN). 1841516929 (St Aubin) (ISBN). 9781841516929 (St Aubin) (ISBN). The Godfrey ed. Relief shown by landforms.;
core