Results 91 to 100 of about 1,318 (189)

AXL promotes malignant phenotypes in tumor cells and might be a potential antitumor target of natural products

open access: yesAdvanced Chinese Medicine, Volume 1, Issue 4, Page 179-189, December 2024.
Abstract AXL belongs to the TAM receptor tyrosine kinase family. Relying on binding its high‐affinity ligand—growth arrest‐specific protein 6 (Gas6)—AXL plays an important role in tumor initiation and progression. Traditional Chinese Medicine (TCM) has been clinically used in tumor treatment for a long time, and remarkable therapeutic efficacy has been
Yuan Yuan   +6 more
wiley   +1 more source

Display Technologies for Expanding the Pharmaceutical Applications of Cyclotides

open access: yesIsrael Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract Cyclotides are ultra‐stable peptides originally discovered in plants based on their medicinal applications. Their natural function is as host defence agents. They are amenable to chemical synthesis for use as scaffolds for drug design applications.
Jing Xie   +4 more
wiley   +1 more source

Oldenlandia umbellata Linnaeus, 1753, spec. nov.

open access: yes
Oldenlandia umbellata, spec. nov. 3. Oldenlandia umbellis nudis lateralibus alternis, foliis linearibus. Fl. zeyl. 67. * Lysimachiae adfinis, saturejae folio, maderaspatensis, capsulis in summitate fere umbellatis. Pluk. alm. 236. t.119.
Linnaeus, Carolus
core   +1 more source

Molecular farming for sustainable production of clinical‐grade antimicrobial peptides

open access: yesPlant Biotechnology Journal, Volume 22, Issue 8, Page 2282-2300, August 2024.
Summary Antimicrobial peptides (AMPs) are emerging as next‐generation therapeutics due to their broad‐spectrum activity against drug‐resistant bacterial strains and their ability to eradicate biofilms, modulate immune responses, exert anti‐inflammatory effects and improve disease management. They are produced through solid‐phase peptide synthesis or in
Shahid Chaudhary   +2 more
wiley   +1 more source

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

open access: yesBMC Genomics, 2010
Background Cyclotides are a family of circular peptides that exhibit a range of biological activities, including anti-bacterial, cytotoxic, anti-HIV activities, and are proposed to function in plant defence.
Suda Jan   +6 more
doaj   +1 more source

Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides

open access: yesChemMedChem, Volume 19, Issue 14, July 15, 2024.
Ancestral sequence reconstruction was used to predict two ancestral cyclotides, Ancy‐m and Ancy‐b. These two predicted ancestors maintained their stability and activities. Meanwhile, Ancy‐b had an improved folding yield over the prototypical bracelet cyclotide.
Zhihao Jiang   +4 more
wiley   +1 more source

Weed Management in Late Kharif Cluster Bean (Cyamopsis tetragonoloba (L.) Taub) and its Impact on Crop Growth and Yield

open access: yesInternational Journal of Bio-Resource and Stress Management, 2023
A field experiment was conducted during kharif 2013-2014 at DWSR-Anand Centre, Anand Agricultural University, Anand (Gujarat) where four herbicides either as sole, integrated with hand weeding (HW) or sequentially applied were evaluated for efficacies ...
Piyush Kumar Saras   +3 more
doaj  

Pollen morphology of some species of Spermacoceae s.s. (Rubiaceae) of the Atlantic Forest, Rio de Janeiro, Brazil

open access: yesActa Botânica Brasílica
This work aimed to morphologically characterize 22 species of Spermacoceae s.s found in the Atlantic Forest in the state of Rio de Janeiro with the purpose of improving palynological knowledge of the studied species.
Vania Gonçalves-Esteves   +4 more
doaj   +1 more source

Ethnobotanical investigation on medicinal plants in Algoz area (South Kordofan), Sudan

open access: yesJournal of Ethnobiology and Ethnomedicine, 2018
Background The inhabitants of western Sudan use traditional medicine for the treatment of various ailments due to lack of medical doctors and unaffordable prices of pharmaceutical products.
Tahani Osman Issa   +6 more
doaj   +1 more source

Image1_Total flavonoids of Oldenlandia diffusa (Willd.) Roxb. suppresses the growth of hepatocellular carcinoma through endoplasmic reticulum stress-mediated autophagy and apoptosis.JPEG

open access: yes, 2022
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumors in the world. Although the current treatment methods for HCC are gradually increasing, its efficacy still cannot meet the medical needs of patients with liver cancer, and new and ...
Huixin Yuan (11960573)   +7 more
core   +1 more source

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