Results 151 to 160 of about 1,001,282 (315)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Oregon LGBTQ+ older adult survey report. Romanian
, 2021 Karen Fredriksen Goldsen, Hyun-Jun Kim, Hailey H. Jung, Adam Davis, Charles A. Emlet.Title from PDF cover (viewed on February 8, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2016 Rocío Fernández-Ballesteros,1 Antonio Bustillos,2 Marta Santacreu,1,3 Rocio Schettini,1 Pura Díaz-Veiga,4 Carmen Huici2 1Clinical and Health Psychology, Universidad Autónoma de Madrid (UAM), 2Social Psychology, Universidad ...
Díaz-Veiga P +5 more
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Oregon LGBTQ+ older adult survey report. Chinese
, 2021 Karen Fredriksen Goldsen, Hyun-Jun Kim, Hailey H. Jung, Adam Davis, Charles A. Emlet.Title from PDF cover (viewed on February 8, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
, 2011 Sexuality in older people is affected by various factors including, sexual physiology in old age, physical illness, medication and mental illness; therefore, a thorough sexual history should form part of a comprehensive psychiatric assessment.
Wattis, John +3 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source