Results 121 to 130 of about 2,637,459 (312)

Efficacy and safety of short-course radiotherapy versus total neoadjuvant therapy in older rectal cancer patients: a randomised pragmatic trial (SHAPERS)

ESMO Gastrointestinal Oncology
Although total neoadjuvant therapy (TNT) is a new standard of care for locally advanced rectal cancer (LARC), there are no data to confirm the safety and efficacy of this approach in older patients.
R. Saúde-Conde, T. Vandamme, M. De Backer, P. Martinive, A. Covas, A. Deleporte, A. Dermine, F. Forget, K. Geboes, Q. Gilliaux, Y. Gokburun, E. Gonne, I. Joye, S. Lecomte, G. Liberale, W. Lybaert, L. Moretti, L. Mortier, S. Mupingu Mwanawa, F. Puleo, E.D. Saad, I. Sinapi, L. Annemans, M. Buyse, F. Sclafani   +24 more
doaj   +1 more source

Preventing Falls in the Elderly [PDF]

, 2017
Falls are the leading cause of fatal and non-fatal injuries for older Americans, leading to 27,000 deaths every year and almost 3 million emergency room visits.
Robbins, Rebecca
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

A Novel Frailty Index Can Predict the Short-Term Outcomes of Esophagectomy in Older Patients with Esophageal Cancer

Current Oncology
Background: Frailty, rather than age, is associated with postoperative morbidity and mortality. We sought to determine whether preoperative frailty as defined by a novel scoring system could predict the outcomes among older patients undergoing ...
Thomas Boerner, Marisa Sewell, Amy L. Tin, Andrew J. Vickers, Caitlin Harrington-Baksh, Manjit S. Bains, Matthew J. Bott, Bernard J. Park, Smita Sihag, David R. Jones, Robert J. Downey, Armin Shahrokni, Daniela Molena   +12 more
doaj   +1 more source

Dental students' knowledge and perception of elderly in relation to geriatric dentistry training [PDF]

, 2009
Dental students need to be equipped with skills, knowledge and positive attitudes while providing dental care to the elderly. Reports from Ministry of Health Malaysia indicated that the prevalence of dental caries and periodontal disease was high among ...
Husna AA,, Robaiyah K,, Tanti IR,
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The prevalence of polypharmacy and hyper-polypharmacy among middle-aged vs. older patients in Saudi Arabia: a cross-sectional study

Frontiers in Pharmacology
IntroductionPolypharmacy, the use of multiple medications, is a growing concern among middle-aged and older patients, posing potential risks and challenges in healthcare management.AimThis study aimed to identify the prevalence of polypharmacy and hyper ...
Aymen A. Alqurain, Murtada Albaharnah, Samanah Al Zayer, Luma Ameer, Sherihan Ghosn, Samaher Al-Shaibi, Marwa Algoraini, Amal Aldhafeeri, Danah A. Alyusuf, Afnan Alshnbari, Nida Alsaffar, Jenan Al-Matouq, Mohammed Al Khamees, Bader AlAlwan, Fadhel A. Alomar   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Rituximab and Fludarabine or Cyclophosphamide Combination Treatment for Older Waldenström Macroglobulinemia Patients

Turkish Journal of Hematology, 2013
Xiaowei Xu, Chun Wang, Yamin Wang, Lili Zhou, Haitao Bai   +4 more
doaj   +1 more source

Patent Foramen Ovale Closure in Special Clinical Situations: More Questions Than Answers?

Life
Patent foramen ovale (PFO) is a remnant of the foetal circulation resulting from incomplete occlusion of the septum primum and septum secundum. Although prevalent in about 25% of the population, it mainly remains asymptomatic.
Anastasios Apostolos, Polyxeni Alexiou, Amalia Papanikolaou, Georgios Trantalis, Maria Drakopoulou, Nikolaos Ktenopoulos, Ioannis Kachrimanidis, Panayotis K. Vlachakis, Ismini Tsakiri, Grigorios Chrysostomidis, Konstantina Aggeli, Costas Tsioufis, Konstantinos Toutouzas   +12 more
doaj   +1 more source