Results 241 to 250 of about 2,637,459 (312)

Prevalence and prognostic relevance of perioperative myocardial injury/infarction after major noncardiac surgery in older patients. [PDF]

Age Ageing
Ergin E, Durak K, Glarner N, Haziri F, Burri-Winkler K, Kaplan E, Huré G, Thommen V, Pargger M, Usai E, Bolliger D, Steiner L, Mujagic E, Lardinois D, Schaeren S, Mueller A, Haller F, Buchmann N, Bischoff-Ferrari HA, Mahfoud F, Strebel I, Gualandro DM, Puelacher C, Mueller C.   +23 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Effects of evidence-based early mobilization on prognostic outcomes in older patients with acute ischemic stroke. [PDF]

Front Public Health
Mao YX, Zhang Y, Wen YH, Hu C.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia. [PDF]

Nutrients
Muchová J, Bolívar-Prados M, Núñez-Lara A, Tomsen N, Clavé P.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk management of cardiovascular disease in older patients with diabetes. [PDF]

Hypertens Res
Sawami K, Tanaka A, Node K.
europepmc   +1 more source

Sarcopenia in Older Patients with Newly Diagnosed Multiple Myeloma.

Gerontology
Sobrini-Morillo P, Corral-Tuesta C, Sánchez-Castellano C, Gutiérrez-Blanco T, Blanchard-Rodríguez MJ, Escudero-González B, Nieto-Góngora C, Moujir López J, Serra-Rexach JA, Cruz-Jentoft AJ.   +9 more
europepmc   +1 more source

Association Between Clinical Frailty and Antibiotic Resistance Among Older Patients with Fever in the Emergency Department. [PDF]

Antibiotics (Basel)
Lim JY, Lee DH, Chung HS, Choi Y, Choi YH, Kim K, Hong KH, Bae SJ.   +7 more
europepmc   +1 more source

Mental health in the peri-hospital period of older patients: the roles of physical symptoms burden and sleep quality. [PDF]

Age Ageing
Smichenko J, Zisberg A, Shochat T.
europepmc   +1 more source