Results 31 to 40 of about 1,087,150 (316)

Falls in older people [PDF]

open access: yesJournal of Electromyography and Kinesiology, 2008
Falls are common incidents, which can have major con-sequences. For example, falls and the interrelated category of accidents being struck by or against objects account for more than 40% of injuries and 30% of injury costs in the USA (Corso et al., 2006).
van Dieen, J.H., Pijnappels, M.A.G.M.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Long-term health conditions and their impact on people with sleep disturbances and dementia

open access: yesBMC Geriatrics
Background Sleep disturbances are common for people with dementia and can be distressing for them and their family. People with dementia live with an average of five other long-term conditions (LTCs).
Penny Rapaport   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unraveling impaired awareness: experiences of people with dementia, Huntington’s disease and Korsakoff’s syndrome, and their informal caregivers

open access: yesBMC Geriatrics
Background Impaired awareness occurs in people with dementia (DEM; Alzheimer’s disease (AD), including mixed AD/vascular), Huntington’s disease (HD) and Korsakoff’s syndrome (KS). We explored the experiences of these people and their informal caregivers,
Hester Fidder   +6 more
doaj   +1 more source

Delirium in older people [PDF]

open access: yesBMJ, 2007
Few ill health situations are more degrading to people of any age than loss of reasoning, faculties, and personhood. These are the unpleasant consequences of delirium—a common condition affecting ill older people, particularly those with some degree of dementia. It is characterised by recent onset of fluctuating inattention and confusion, linked to one
John, Young, Sharon K, Inouye
openaire   +2 more sources

The use of telephone befriending in low level support for socially isolated older people – an evaluation

open access: yes, 2010
There is increasing policy recognition that the alleviation of social isolation and loneliness in older people should be prioritised. Recently, technology, such as telephone networks and the Internet, has received attention in supporting isolated and ...
Cattan, Mima   +8 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Audit and group feedback in nursing home physician groups: lessons learned from a qualitative study

open access: yesBMC Health Services Research
Background Audit and group feedback (A&F) is an instrument used to encourage healthcare professionals to improve the quality of care. Clinical practice was audited against a set of criteria and fed back to a group by a facilitator.
Gary Y. C. Yeung   +5 more
doaj   +1 more source

Reflections of older people living in nursing homes

open access: yes, 2014
AimTo explore experiences of ageing in older people living in nursing homes, based on the gerotranscendence theory.MethodInterviews were held with 14 people aged between 80 and 96 years.
Melin-Johansson, Christina,   +6 more
core   +1 more source

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