Results 1 to 10 of about 113,645 (287)

Intravenous Thrombolytic Treatment in the Oldest Old [PDF]

Stroke Research and Treatment, 2012
Background and Purpose. Intravenous thrombolysis using tissue plasminogen activator is safe and probably effective in patients >80 years old. Nevertheless, its safety has not been specifically addressed for the oldest old patients (≥85 years old, OO). We
Juan García-Caldentey, María Alonso de Leciñana, Patricia Simal, Blanca Fuentes, Gemma Reig, Fernando Díaz-Otero, Marta Guillán, Ana García, Patricia Martínez, Andrés García-Pastor, José Antonio Egido, Exuperio Díez-Tejedor, Antonio Gil-Núñez, José Vivancos, Jaime Masjuan   +14 more
doaj   +8 more sources

Consensus expert opinion on key items in planning and designing clinical trials in geriatric patients

Российский журнал гериатрической медицины, 2022
The consensus statement provides expert opinion on key items in planning and designing clinical trials for medications that are intended for use mainly or probably in geriatric patients.
O. N. Tkacheva, D. A. Sychev, I. P. Malaya, V. A. Burmistrov, E. K. Vergazova, A. A. Galeeva, I. G. Gordeev, V. A. Dmitriev, M. V. Zhuravleva, S. K. Zyryanov, Yu. V. Kotovskaya, A. V. Naumov, S. V. Nedogoda, N. K. Runikhina, К. Е. Teplova-Bareisha, E. V. Frolova, A. L. Khokhlov   +16 more
doaj   +1 more source

Short- and long-term survival after curative resection for colorectal cancer in nonagenarian patients

Asian Journal of Surgery, 2022
Background/objective: With increased life expectancy, the incidence of colorectal cancer in oldest-old patients has been rising. Advanced age is a risk factor for adverse outcomes after surgery.
Shintaro Hashimoto, Kiyoaki Hamada, Yorihisa Sumida, Masato Araki, Kouki Wakata, Tota Kugiyama, Ayako Shibuya, Masato Nishimuta, Shigeyuki Morino, Masayuki Baba, Soichiro Kiya, Keisuke Ozeki, Akihiro Nakamura   +12 more
doaj   +1 more source

Determining the Factors Affecting the Development of Perioperative Complications According to Aging Stages

Bagcilar Medical Bulletin, 2022
Objective:This study aimed to examine perioperative complication risks in elderly patients stratified by age.Method:Elderly patients (youngest-old, ages 65 to 74 years; middle-old, 75 to 84 years; and oldest-old, ≥85 years) and controls (20-30 years) who
Meliha Orhon Ergün, Seniyye Ülgen Zengin, Pelin Çorman Dinçer, Tümay Umuroğlu, Zuhal Aykaç   +4 more
doaj   +1 more source

Does Estimated Glomerular Filtration Rate Predict In-Hospital Mortality in Acutely Unwell Hospitalized Oldest Old?

Geriatrics, 2022
Globally the population of older adults is the fastest growing age group. Estimated glomerular filtration rate (eGFR) is an estimation of true kidney function with lower eGFR associated with higher mortality.
Zack Robert Wakerly, Roy L. Soiza, Tiberiu A. Pana, Phyo Kyaw Myint   +3 more
doaj   +1 more source

Physical activity and depression in older adults in times of the COVID-19 pandemic

Baltic Journal of Health and Physical Activity, 2021
Background: During the COVID-19 pandemic that affected the whole world, individuals aged 65 and over were in the group of “leaving home restriction” for a long time.
İnci Kesi̇lmi̇ş, Gülten Geçi̇tli̇, Seda Kavak , Süleyman Kostal, Mehmet Melih Kesi̇lmi̇ş   +4 more
doaj   +1 more source

Hip Fracture in Asia with a Special Focus in the Oldest Old: A Brief Review

Journal of Clinical Rheumatology and Immunology, 2022
Osteoporosis is a prevalent disease globally, with fragility fracture being the clinical outcome. Hip fracture is mostly associated with morbidity, immobility, and mortality among all fragility fractures.
Ching-Lung Cheung, Shun-Cheong Ho, Suhas Krishnamoorthy, Xiaowen Zhang   +3 more
doaj   +1 more source

Associations between constipation, overeating, and depression: A survey of Chinese oldest-old and centenarians

Heliyon, 2022
Objectives: Depression is a common disease of elderly population, with a global prevalence of more than 20%. Few studies have involved the associations of constipation and overeating with depression, especially in the elderly population.
Zhigao Sun, Xin Su, Xiaoqian Zhao, Yao Yao, Yali Zhao, Pei Zhang, Zhirui Li, Shihui Fu   +7 more
doaj   +1 more source

Prognosis and quality of life of elderly patients after intensive care

Swiss Medical Weekly, 2012
Ageing of the world’s population raises important questions about the utilisation of the health care system. It is not clear how much should be invested in the last years of life whereas the costs are known to increase in parallel.
Marco Conti, Paolo Merlani, Bara Ricou
doaj   +1 more source

Associations of poor oral health with frailty and physical functioning in the oldest old: results from two studies in England and Japan

BMC Geriatrics, 2021
Background Very few studies have examined the relationship of oral health with physical functioning and frailty in the oldest old (> 85 years). We examined the association of poor oral health with markers of disability, physical function and frailty in ...
Viviana Albani, Kensuke Nishio, Tomoka Ito, Eftychia Kotronia, Paula Moynihan, Louise Robinson, Barbara Hanratty, Andrew Kingston, Yukiko Abe, Michiyo Takayama, Toshimitsu Iinuma, Yasumichi Arai, Sheena E. Ramsay   +12 more
doaj   +1 more source