Results 71 to 80 of about 113,993 (287)

Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes. [PDF]

open access: yes, 2013
Factor structure analyses have revealed the presence of specific biological system markers in healthy humans and diseases. However, this type of approach in very old persons and in type 2 diabetes (T2DM) is lacking.
Abbatecola, AM   +17 more
core   +1 more source

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost   +10 more
wiley   +1 more source

Ageing, Health and Life Satisfaction of the Oldest Old: An Analysis for Germany [PDF]

open access: yes
This analysis uses data from the German Socio-Economic Panel (GSOEP) and the Survey on Health, Ageing and Retirement in Europe (SHARE) to assess the effect of ageing and health on the life satisfaction of the oldest old (defined as 75 and older).
Gwozdz, Wencke, Sousa-Poza, Alfonso
core  

Physical Exercise in the Oldest Old

open access: yesComprehensive Physiology, 2019
AbstractSocieties are progressively aging, with the oldest old (i.e., those aged >80–85 years) being the most rapidly expanding population segment. However, advanced aging comes at a price, as it is associated with an increased incidence of the so‐called age‐related conditions, including a greater risk for loss of functional independence.
Valenzuela Ruiz, Pedro Luis   +6 more
openaire   +4 more sources

Risk of Traumatic Intracranial Hemorrhage From Low-Energy Falls in the Oldest-Old Patients

open access: yesAnnals of Geriatric Medicine and Research, 2016
Background: The population of individuals classified as oldest-old (aged ≥85 years) has increased rapidly in recent years. The rates of morbidity from chronic diseases and physical dependence tend to be higher in the oldest-old compared with individuals ...
Sung Kyu Kim   +5 more
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

The association between resilience and survival among Chinese elderly [PDF]

open access: yes
Based on the unique longitudinal data of the elderly aged 65+ with a sufficiently large sub-sample of the oldest-old aged 85+ from the Chinese Longitudinal Healthy Longevity Survey, we construct a resilience scale with 7 indicators for the Chinese ...
Ke Shen, Yi Zeng
core  

Analysis of health and longevity in oldest-old population: a health capital approach [PDF]

open access: yes, 2005
Using 2002 cross-sectional data and 1998, 2000, 2002 three waves of panel data from the Chinese Longitudinal Healthy Longevity Survey, we study health in oldest old population.
Zhao, Zhong
core  

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

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