Results 131 to 140 of about 735,066 (303)

Age-related changes in sleep spindle characteristics in individuals over 75 years of age: a retrospective and comparative study

BMC Geriatrics
Background Sleep and its architecture are affected and changing through the whole lifespan. We know main modifications of the macro-architecture with a shorter sleep, occurring earlier and being more fragmented.
Bastien Poirson, Pierre Vandel, Hubert Bourdin, Silvio Galli   +3 more
doaj   +1 more source

Asymptotic Giant Branch Stars in the Leo I Dwarf Spheroidal Galaxy

, 2010
Twenty six Asymptotic Giant Branch (AGB) variables are identified in the Local Group galaxy Leo I. These include 7 Mira and 5 semi-regular variables for which periods, amplitudes and mean magnitudes are determined.
Azzopardi, Bellazzini, Cutri, Demers, Dolphin, Feast, Feast, Feast, Gallart, Glatt, Gratton, Gullieuszik, Held, Held, Hernandez, John W. Menzies, Karakas, Kato, Koch, Lagadec, Marigo, Mateo, Menzies, Menzies, Michael W. Feast, Mucciarelli, Mucciarelli, Nishida, Noriyuki Matsunaga, Patricia A. Whitelock, Salaris, Schechter, Shetrone, Van Leeuwen, Whitelock, Whitelock, Whitelock, Whitelock, Wood   +38 more
core   +1 more source

Successful aging Among the Oldest Old

, 2018
Vuosisatojen ajan ihmiset ja yhteiskunnat ovat tavoitelleet pidempää ja terveempää elämä ja parempaa elämän laatua. Nyt 21. vuosisadalla voimme todistaa vanhuusiän kuolleisuuden nopeaa laskua ja hyvin vanhan ikäryhmän ennennäkemätöntä kasvua. Elämän pidentyminen ei kuitenkaan välttämättä merkitse parempaa terveyttä ja elämän laatua.
openaire   +3 more sources

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Kidney function and cognitive decline in an oldest-old Chinese population

Clinical Interventions in Aging, 2017
Kunhao Bai,1,2,* Yujing Pan,3,* Fanghong Lu,4 Yingxin Zhao,4 Jinwei Wang,1,2 Luxia Zhang1,2 1Renal Division, Department of Medicine, Peking University First Hospital, Beijing, People’s Republic of China; 2Peking University Institute of Nephrology,
Bai K, Pan Y, Lu F, Zhao Y, Wang J, Zhang L   +5 more
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Functioning and quality of life in Dutch oldest old with diverse levels of dependency

Patient Preference and Adherence, 2018
Riaan Botes,1 Karin M Vermeulen,1 Antonie M Gerber,2 Adelita V Ranchor,3 Erik Buskens11Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; 2Department of Basic Medical Sciences (G25 ...
Botes R, Vermeulen KM, Gerber AM, Ranchor AV, Buskens E   +4 more
doaj  

Factors associated with mobility of the oldest old

Fisioterapia em Movimento
Introduction: Several factors can be associated to the reduction of mobility among the elderly. Early identification of these factors is crucial, since it may lead to prevention of functional dependencies. Objective: To analyze the association between
Vanessa Ribeiro dos Santos, Diego Giulliano Destro Christofaro, Igor Conterato Gomes, Ismael Forte Freitas Júnior, Luís Alberto Gobbo   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mortality statistics for the oldest-old

Demographic Research, 2000
The main purposes of this paper is to evaluate the quality of Canadian data among the oldest-old (80+) over the 1951-1995 period, and to compare estimations of Canadian probabilities of death based on the extinct generation method with those of other ...
doaj