Results 41 to 50 of about 735,066 (303)

Association between medical resources and the proportion of oldest-old in the Chinese population

Military Medical Research, 2021
The potential association between medical resources and the proportion of oldest-old (90 years of age and above) in the Chinese population was examined, and we found that the higher proportion of oldest-old was associated with the higher number of beds ...
Chao Tan, Cai-Zhi Tang, Xing-Shu Chen, Yong-Jun Luo   +3 more
doaj   +1 more source

Diagnosing dementia in the oldest-old [PDF]

Maturitas, 2011
The "oldest-old" comprise the fastest growing segment of the population in much of the world. Rates of dementia are extremely high in this age group and will present a major public health burden as the numbers of these individuals quadruple by the middle of the century.
Brumback-Peltz, Carrie, Balasubramanian, Archana B, Corrada, María M, Kawas, Claudia H   +3 more
openaire   +4 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Cognitive Decline and Dementia in the Oldest-Old

Rambam Maimonides Medical Journal, 2012
The oldest-old are the fastest growing segment of the Western population. Over half of the oldest-old will have dementia, but the etiology is yet unknown. Age is the only risk factor consistently associated with dementia in the oldest-old.
Efrat Kravitz, James Schmeidler, Michal Schnaider Beeri   +2 more
doaj   +1 more source

Changes of Dentario Glanduleosae-Fagetum Forest Stand in Roztocze National Park, South Eastern Poland From 1946 To 2001 [PDF]

, 2010
Roztocze Nation Park (RNP) is located in the central part of Roztocze, a hilly region in south-eastern Poland. The most important type of forest community in RNP is Dentario glandulosae-Fagetum. Potential and real vegetation, as well as forest stand maps
Tracz, Justyna
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

COVID in oldest old: What we learnt in a tertiary care hospital emergency

Archives of Gerontology and Geriatrics Plus
Background: COVID-19 created extreme havoc among the elderly and the oldest-old bore the maximum brunt during triaging. With COVID cases again on the raise, this retrospective analysis gives an insight of the clinical spectrum and mortality in COVID-19 ...
Tejeswini CJ, Vinaya Rani G, Jehath Syed, Prathiba Pereira, Pankaja S S, Shwethashree MS, Basavanagowdappa H   +6 more
doaj   +1 more source

Predicting Survival in Oldest Old People

The American Journal of Medicine, 2012
Measures of physical performance are regarded as useful objective clinical tools to estimate survival in elderly people. However, oldest old people, aged 85 years or more, are underrepresented in earlier studies and frequently unable to perform functional tests.
Taekema, D.G., Gussekloo, J., Westendorp, R.G.J., Craen, A.J.M. de, Maier, A.B.   +4 more
openaire   +5 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source