Results 71 to 80 of about 2,970,330 (220)

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Physiological barriers to oral intake in survivors of critical illness: A scoping review

Nutrition in Clinical Practice, EarlyView.
Abstract Oral nutrition is the predominant mode of nutrition delivery on the post–Intensive Care Unit (ICU) ward; yet, it is associated with lower intake than via enteral or parenteral nutrition. There are limited data on barriers that influence oral intake in ICU survivors.
Breanna J. Teleki, Elizabeth Viner Smith, Amy Freeman‐Sanderson, Rosalie Yandell, Lee‐anne S. Chapple   +4 more
wiley   +1 more source

Exploring New Chemical Paths in Quantum AI: Preliminary Accomplishments and Future Perspectives

Advanced Quantum Technologies, EarlyView.
Two new strategies derived from Chemical AI to promote the advancement of sustainable quantum technologies are presented and discussed. The first strategy relies on the chemical implementation of molecular fuzzy sets, which are quantum mixed states associated with chemical microheterogeneous systems. The second strategy relies on photochromic compounds
Pier Luigi Gentili
wiley   +1 more source

Depression, Olfaction, and Quality of Life: A Mutual Relationship

Brain Sciences, 2018
Olfactory dysfunction has been well studied in depression. Common brain areas are involved in depression and in the olfactory process, suggesting that olfactory impairments may constitute potential markers of this disorder.
Marion Rochet, Wissam El-Hage, Sami Richa, François Kazour, Boriana Atanasova   +4 more
doaj   +1 more source

Progress of MXenes‐based responsive materials for soft sensors and actuators

Responsive Materials, EarlyView.
MXene, a promising 2D material, excels at mimicking human sensing and feedback system, making it ideal for intelligent robots. This review first covers its structure, properties, and synthesis. It then summarizes recent MXene‐based sensors and actuator.
Peidi Zhou, Wenjie Yang, Yihan Qiu, Meiping Xu, Leiting Liao, Xinlei Gong, Chan Zheng, Minghua You, Cheng Zhang, Huamin Chen, Mingcen Weng   +10 more
wiley   +1 more source

Olfaction, psychiatric disorders and autoimmunity: Is there a common genetic association?

Autoimmunity, 2009
Psychiatric diseases are often associated with mild alterations in immune functions (e.g., schizophrenia) as well as autoimmune features. Recent evidence suggests that autoimmune diseases (AD) demonstrate a higher prevalence of psychiatric disorders, such as depression and psychosis, than in the normal population.
Oscar-Danilo, Ortega-Hernandez, Shaye, Kivity, Yehuda, Shoenfeld   +2 more
openaire   +2 more sources

Illicit Drug‐Derived Volatile Organic Compounds as Markers for Application in Noncontact Detection Technology

The Chemical Record, EarlyView.
This review highlights the characteristic odor markers of illicit drugs, emphasizing volatile markers from both natural and synthetic sources, and explores the shift from canine‐based detection to emerging noncontact sensing technologies. Illicit drug use remains a global concern, requiring effective detection methods to counter evolving concealment ...
Minwoo Kim, Solpa Lee, Anmo J. Kim, Cong Wang, Yongwoo Jang   +4 more
wiley   +1 more source

Functional and Morphological Changes in the Olfactory Epithelium of Mouse Models With Upper Respiratory Inflammation and Olfactory Dysfunction [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives This study evaluated behavioral test results and histological findings in murine models of allergic rhinitis (AR), chronic rhinosinusitis (CRS), and drug-induced anosmia, comparing outcomes among groups.
Shin Hyuk Yoo, Jun-Sang Bae, Reiza Ventura, Eun Hee Kim, A Young Kim, Ji Hye Kim, Ji-hun Mo   +6 more
doaj   +1 more source

Interrelatedness of Neurocognitive Domain Functioning Between Unprompted and Prompted Identification Testing With Psychophysical Olfactory Evaluation in a Post‐COVID‐19 Cohort

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Assessment of olfactory function with psychophysical testing requires cognitive demand to correctly pair test odors with remembered scents. Individuals suffering from long‐Corona Virus Disease 2019 (long‐COVID‐19) may develop a decline in neurocognitive performance, which may be concurrent with persistent olfactory dysfunction (OD ...
Jeremy P. Tervo, Patricia T. Jacobson, Brandon J. Vilarello, Tiana M. Saak, Francesco F. Caruana, Liam W. Gallagher, Joseph B. Gary, David A. Gudis, Paule V. Joseph, Tse‐Hwei Choo, Davangere P. Devanand, Terry E. Goldberg, Jonathan B. Overdevest   +12 more
wiley   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source