Results 111 to 120 of about 1,396,394 (289)

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

Advanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang, Jun Liu, Qi Zhao, Huilong Yin, Angang Yang, Minhua Zheng, Rui Zhang   +6 more
wiley   +1 more source

Impact of medication use on olfactory performance in older adults

Frontiers in Public Health
IntroductionOlfactory dysfunction impacts quality of life, safety, and nutrition. Despite its relevance among older adults, the role of medications in influencing olfactory performance remains understudied.
Maite Izco-Cubero, Maite Izco-Cubero, Fabiola Zambom-Ferraresi, Fabiola Zambom-Ferraresi, Fabiola Zambom-Ferraresi, Fabiola Zambom-Ferraresi, Fabricio Zambom-Ferraresi, Fabricio Zambom-Ferraresi, Fabricio Zambom-Ferraresi, Fabricio Zambom-Ferraresi, Fabricio Zambom-Ferraresi, María Luisa Fernández González de la Riva, María Luisa Fernández González de la Riva, Enrique Santamaría, Enrique Santamaría, Enrique Santamaría, Enrique Santamaría, Joaquín Fernandez-Irigoyen, Joaquín Fernandez-Irigoyen, Joaquín Fernandez-Irigoyen, Joaquín Fernandez-Irigoyen, Mercedes Lachén-Montes, Juan Jose Lasarte, Juan Jose Lasarte, Juan Jose Lasarte, Maria Uzcanga-Lacabe, Maria Uzcanga-Lacabe, Secundino Fernandez, Gloria Sanjurjo San Martin, Enrique Maraví-Aznar, Enrique Maraví-Aznar, Nicolas Martinez-Velilla, Nicolas Martinez-Velilla, Nicolas Martinez-Velilla, Nicolas Martinez-Velilla, Nicolas Martinez-Velilla, Nicolas Martinez-Velilla   +36 more
doaj   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Complementary Sensory and Associative Microcircuitry in Primary Olfactory Cortex [PDF]

, 2011
The three-layered primary olfactory (piriform) cortex is the largest component of the olfactory cortex. Sensory and intracortical inputs converge on principal cells in the anterior piriform cortex (aPC).Wecharacterize organization principles of the ...
Dietmar Schmitz, Wiegand, H.F., Beed, P., Wiegand, Hauke F., Leibold, Christian, Leibold, C., Bendels, Michael H. K., Bendels, M.H., Schmitz, Dietmar, Michael H. K. Bendels, Christian Leibold, Johenning, Friedrich W., Prateep Beed, Friedrich W. Johenning, Johenning, F.W., Beed, Prateep, Hauke F. Wiegand, Schmitz, D.   +17 more
core   +1 more source

Frequency of Oral Lesions, Olfactory, and Gustatory Disorders and Xerostomia in Patients with COVID-19

Dentistry Journal
COVID-19, a respiratory illness with a global impact on millions, has recently been linked to manifestations affecting various bodily systems, including the oral cavity.
Natália Lopes Castilho, Daniella R. Barbosa Martelli, Renato Assis Machado, Zêus Araujo Cunha, Claudiojanes dos Reis, Priscila Regina Queiroz, Dayane de Sá Silva, Eduardo Araujo Oliveira, Ricardo D. Coletta, Hercílio Martelli-Júnior   +9 more
doaj   +1 more source

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker, Mabel Berg, Nicolaus Knight, Jessica W. Grayson, Bradford A. Woodworth, Justin H. Turner, Do‐Yeon Cho   +6 more
wiley   +1 more source

North American Delphi Consensus Study on Sinonasal Malignancy Survivorship Care

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Survival for patients with sinonasal cancers has improved over the past decades, but there are no dedicated survivorship guidelines for this cohort. Objective To understand experts’ priorities and perspectives on key survivorship tenets (surveillance, second tumor screening, toxicity, and symptom management).
Matheus Sewastjanow‐Silva, Samagra Jain, Rita Snyder, Erin L. McKean, Ralph Abi Hachem, Nithin D. Adappa, J. Ken Byrd, Ricardo L. Carrau, Marc A. Cohen, Ivan H. El‐Sayed, Mathew N. Geltzeiler, Ehab Y. Hanna, Edward C. Kuan, Nyall R. London Jr., Zoukaa B. Sargi, Carl H. Snyderman, Marilene B. Wang, Ian J. Witterick, Shirley Y. Su   +18 more
wiley   +1 more source

Associations Between Multiple Chemosensory Dysfunction and Cognition

International Forum of Allergy &Rhinology, EarlyView.
Key Points This study supports the association between chemosensory dysfunction and cognition. We introduce methods of assessing trigeminal function with the Medoc TSA‐II thermoprobe. Our results identify an association between subjective trigeminal dysfunction and cognition.
Michelle Yu, Stephanie M. Horton, Tiffany Chen, Shaun A. Nguyen, Zachary M. Soler, Rodney J. Schlosser   +5 more
wiley   +1 more source

Prejuízo no processamento olfatório emocional em um modelo animal de doença de Parkinson e o ambiente de criação como estratégia protetora [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011Os sintomas pré-motores da doença de Parkinson (DP) englobam diversas alterações emocionais ...
França, Sanmara de Lima
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