Results 101 to 110 of about 1,396,394 (289)

Nicotine as an odorant : a biochemical and electrophysiological study of receptors for nicotine in the olfactory epithelium of the rat [PDF]

The results suggest that nicotine vapour stimulates an in vitro olfactory preparation in three strains of rat and two strains of mouse, in a manner similar to known odorants.
Edwards, Damian Andrew
core  

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

Postviral Olfactory Disorder

Korean Journal of Otorhinolaryngology-Head and Neck Surgery, 2010
후각은 오감 중의 하나로 주변에 존재하는 다양한 냄새(odor)나 향기(fragrance)를 맡고, 음식의 맛을 느끼며, 상한 음식이나 화재의 발생, 가스나 독성 물질의 누출과 같은 위험한 상황을 인지하는 등 인간의 생활에 중요한 역할을 한다. 또한 실제 정상 후각 기능이 반드시 필요한 직업(요리사, 소방관, 맛 감식가, 다양한 산업체 근로자 등)에서는 생활을 영위하는 중요한 수단으로 작용하며, 후각 감퇴나 후각 소실 등의 후각 장애가 발생 시 심각한 악영향을 미치게 된다. 이러한 후각 장애는 정상적인 노화 과정에서부터 다양한 질환 등에 의해서 발생할 수 있다.
openaire   +1 more source

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

Main causes and diagnostic evaluation in patients with primary complaint of olfactory disturbances

Brazilian Journal of Otorhinolaryngology, 2014
INTRODUCTION: Establishing a diagnosis in patients with olfactory disturbances has always been challenging for physicians.One reason for this is the rarity of some of the diseases that affect this sense, such as Kallmann's syndrome and post-viral ...
Marco Aurélio Fornazieri, Bruno Barros Pinto Borges, Thiago Freire Pinto Bezerra, Fábio de Rezende Pinna, Richard Louis Voegels   +4 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Insights about the Olfactory Bulb Structural organization and dysfunction [PDF]

Arcades of Medicine
The olfactory bulb (OB) is a critical structure for the sense of olfaction, processing olfactory information from the nose to the brain. The OB's is characterized by layered organization that facilitates olfactory processing.
Mostafa Daboos, Nevine Soliman, Samaa Kamar, Lobna Elkhateb   +3 more
doaj   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

ASSESSMENT OF THE DIAGNOSTIC VALUE OF THE METHOD OF COMPUTER OLFACTOMETRY

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2019
Olfactory studies can be a criterion for evaluating rhinosurgical intervention, and olfactory impairment may indicate respiratory impairment. Therefore, the urgent task is to develop an integrated approach to determining respiratory and olfactory ...
Oleg Avrunin, Yana Nosova, Sergii Zlepko, Ibrahim Younouss Abdelhamid , Nataliia Shushliapina   +4 more
doaj   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source