This study demonstrates that high radiological severity in patients with CRSwNP is uniquely characterized by a mixed Type 2 and Type 3 epithelial inflammatory signature. These findings suggest that severe disease involves a complex immune endotype, providing new insights into precision therapeutic strategies for refractory CRSwNP.
Guangfu Xu +5 more
wiley +1 more source
Olfactory mucosa in the nose (dog)
Stain: Iron Hematoxylin and eosin (Heidenhain). The pseudostratified epithelium of the olfactory mucosa contains sensory cells, support cells and basal cells.
Poels, Lambert G.
core
Chronic interleukin-13 expression in mouse olfactory mucosa results in regional aneuronal epithelium. [PDF]
Saraswathula A +3 more
europepmc +1 more source
Olfactory Outcomes After Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis
ABSTRACT Objective To evaluate subjective and objective olfactory outcomes in patients undergoing endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). Methods Prospective, single‐center study including adult patients undergoing ESS for CRSwNP from July 2022 to May 2024.
Elysia Grose +4 more
wiley +1 more source
PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt-Jakob Disease. [PDF]
Cazzaniga FA +28 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Intranasally applied human olfactory mucosa neural progenitor cells migrate to damaged brain regions. [PDF]
Kronner JM +5 more
europepmc +1 more source
Role and Mechanism of Olfactory Stem Cells in the Treatment of Olfactory Disorders
Olfactory dysfunction is one of the most prevalent diseases in otorhinolaryngology, particularly since the coronavirus 2019 (COVID-19) pandemic, with a potential impact on daily life.
Shengqi Gan +5 more
doaj +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source
An Update on Sphingosine-1-Phosphate and Lysophosphatidic Acid Receptor Transcripts in Rodent Olfactory Mucosa. [PDF]
Toebbe JT, Genter MB.
europepmc +1 more source

