Results 141 to 150 of about 447,033 (267)

Position Paper on Olfactory Dysfunction [PDF]

, 2017
Background: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in
Altundag, A, Andrews, P, Cinghi, C, Costanzo, RM, Damm, M, Frasnelli, J, Gudziol, H, Gupta, N, Haehner, A, Holbrook, E, Hong, SC, Hornung, D, Hummel, T, Hüttenbrink, KB, Kamel, R, Kobayashi, M, Konstantinidis, I, Landis, BN, Leopold, DA, Macchi, A, Miwa, T, Moesges, R, Mueller, CA, Mullol, J, Ottaviano, G, Passali, GC, Philpott, C, Pinto, JM, Ramakrishnan, VJ, Rombaux, P, Roth, Y, Schlosser, RA, Shu, B, Soler, G, Stjärne, P, Stuck, BA, Vodicka, J, Welge-Luessen, A, Whitcroft, KL   +38 more
core   +2 more sources

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

The dual origin of the peripheral olfactory system: placode and neural crest

Molecular Brain, 2011
Background The olfactory epithelium (OE) has a unique capacity for continuous neurogenesis, extending axons to the olfactory bulb with the assistance of olfactory ensheathing cells (OECs).
Katoh Hiroyuki, Shibata Shinsuke, Fukuda Kimiko, Sato Momoka, Satoh Etsuko, Nagoshi Narihito, Minematsu Takeo, Matsuzaki Yumi, Akazawa Chihiro, Toyama Yoshiaki, Nakamura Masaya, Okano Hideyuki   +11 more
doaj   +1 more source

The Olfactory Mucosa of the Sheep [PDF]

Australian Journal of Biological Sciences, 1970
The olfactory mucosa of the sheep was studied by light and electron microscopy. The epithelium conforms to the general vertebrate pattern and consists of olfactory receptor cells, supporting, and basal cells. The free edge of the epithelium is made up of long microvilli from the supporting cells and olfactory rods of the receptor cells, each carrying ...
openaire   +2 more sources

The Chemical Senses [PDF]

, 2015
Long-standing neglect of the chemical senses in the philosophy of perception is due, mostly, to their being regarded as ‘lower’ senses. Smell, taste, and chemically irritated touch are thought to produce mere bodily sensations ...
Smith, Barry C.
core  

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

OC-163 identification of inflammatory bowel disease (IBD) using field asymmetric ion mobility spectrometry (FAIMS) [PDF]

, 2012
Introduction Resident colonic bacteria, principally anaerobes and firmicutes, ferment undigested fibre. The resultant volatile organic compounds (VOCs) formed are dissolved in the faeces but also absorbed and excreted in the urine.
Arasaradnam, Ramesh P., Bardhan, Karna Dev, Covington, James A., Hetherington, E., Nwokolo, Chuka U., Ouaret, N., Quraishi, M. N., Thomas, M. G.   +7 more
core   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C)

Cell and Tissue Research, 2014
The pathogenesis of postviral olfactory disorder (PVOD) has not been fully elucidated. We investigated morphological changes and innate immune responses in the mouse olfactory mucosa induced by intranasal administration of polyinosinic-polycytidylic acid
K. Kanaya, K. Kondo, K. Suzukawa, Takashi Sakamoto, Shu Kikuta, Kazunari Okada, T. Yamasoba   +6 more
semanticscholar   +1 more source