Results 161 to 170 of about 447,033 (267)

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Acute Transplantation of Human Olfactory Mucosa-Derived Olfactory Ensheathing Cells Fails to Improve Locomotor Recovery in Rats

Acta Medica Iranica, 2018
Olfactory ensheathing cells-based therapy for spinal cord injury (SCI) repair has been a possible treatment for clinical study because of their safety in autologous transplantation and potential regenerative capability.
Mina Afhami, Mansoureh Hashemi, Khashayar Afshari, Jamal Chenari, Seyed Mohammad Tavangar, Mahmoudreza Hadjighassem, Ahmad Reza Dehpour, Ahad Muhammadnejad, Arvin Haj-Mirzaian, Vafa Rahimi-Movaghar   +9 more
doaj  

Identification of Immune Cells in Murine Olfactory Mucosa. [PDF]

Methods Mol Biol, 2023
Wellford SA, Moseman EA.
europepmc   +1 more source

Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age‐Associated Gut–Brain Axis Profiles

Aging Cell, Volume 25, Issue 5, May 2026.
Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni, Jonas Mingaila, Gediminas Alzbutas, Rokas Lukoševičius, Justinas Drūteika, Kamila Łuczyńska, Rima Ramonaitė, Tadeusz Pietras, Kasper Sipowicz, Dovilė Kiudelytė, Karolina Keršytė, Emilija Keževičiūtė, Greta Najūtė, Juozas Kupčinskas, Jordi Mayneris‐Perxachs, Daiva Baltriukienė, Aurelijus Burokas   +16 more
wiley   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, Volume 81, Issue 5, Page 1617-1634, May 2026.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Human-derived air-liquid interface cultures decipher Alzheimer's disease-SARS-CoV-2 crosstalk in the olfactory mucosa. [PDF]

J Neuroinflammation, 2023
Shahbaz MA, Kuivanen S, Lampinen R, Mussalo L, Hron T, Závodná T, Ojha R, Krejčík Z, Saveleva L, Tahir NA, Kalapudas J, Koivisto AM, Penttilä E, Löppönen H, Singh P, Topinka J, Vapalahti O, Chew S, Balistreri G, Kanninen KM.   +19 more
europepmc   +1 more source

Olfactory mucosa sampling and processing v1

, 2022
This protocol describes the olfactory mucosa sampling and processing for RT-QuIC assays and was adapted from A. Stefani et al. (doi:10.1093/brain/awab005).
openaire   +1 more source

Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients. [PDF]

Int J Mol Sci, 2022
Lampinen R, Górová V, Avesani S, Liddell JR, Penttilä E, Závodná T, Krejčík Z, Lehtola JM, Saari T, Kalapudas J, Hannonen S, Löppönen H, Topinka J, Koivisto AM, White AR, Giugno R, Kanninen KM.   +16 more
europepmc   +1 more source

Corrigendum: PMCA-based detection of prions in the olfactory mucosa of patients with sporadic Creutzfeldt-Jakob disease. [PDF]

Front Aging Neurosci, 2023
Cazzaniga FA, Bistaffa E, De Luca CMG, Portaleone SM, Catania M, Redaelli V, Tramacere I, Bufano G, Rossi M, Caroppo P, Giovagnoli AR, Tiraboschi P, Di Fede G, Eleopra R, Devigili G, Elia AE, Cilia R, Fiorini M, Bongianni M, Salzano G, Celauro L, Quarta FG, Mammana A, Legname G, Tagliavini F, Parchi P, Zanusso G, Giaccone G, Moda F.   +28 more
europepmc   +1 more source

Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries. [PDF]

World J Clin Cases, 2023
Stepanova OV, Fursa GA, Andretsova SS, Shishkina VS, Voronova AD, Chadin AV, Karsuntseva EK, Reshetov IV, Chekhonin VP.   +8 more
europepmc   +1 more source