Results 221 to 230 of about 393,252 (329)

Curcumin-primed olfactory mucosa-derived mesenchymal stem cells mitigate cerebral ischemia/reperfusion injury-induced neuronal PANoptosis by modulating microglial polarization.

open access: yesPhytomedicine
Ziwei Lan   +12 more
semanticscholar   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

open access: yesThe Journal of Pathology, Volume 266, Issue 4-5, Page 369-389, August 2025.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk   +5 more
wiley   +1 more source

Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer

open access: yesSmall Science, Volume 5, Issue 8, August 2025.
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh   +2 more
wiley   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin   +4 more
wiley   +1 more source

Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Deficiency of Chil4 impairs OE homeostasis through loss of sustentacular cells and a specific type of immature sensory neuron, cell cycle arrest in globose basal cells, and inflammatory activation in microglia‐like cells. ABSTRACT Mammalian olfactory epithelium (OE) undergoes consistent self‐renewal throughout life.
Tingting Wu   +7 more
wiley   +1 more source

Omicron Impacts Olfaction in Hamsters

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Compared to the original SARS‐CoV‐2 strain (D614G), infection by Omicron: still decreases olfactory performance in hamster; infects the olfactory epithelium with a delay and to a lesser extent; induces a strong inflammation with a delay; induces much less olfactory epithelium damage; still provokes release of cellular debris in the lumen of the nasal ...
Virginie Guérin   +9 more
wiley   +1 more source

Through The Back Door: Expiratory Accumulation of SARS-Cov-2 in the Olfactory Mucosa as Mechanism for CNS Penetration. [PDF]

open access: yesInt J Med Sci, 2021
Pipolo C   +7 more
europepmc   +1 more source

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