Results 211 to 220 of about 448,986 (295)

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

open access: yesBrain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo   +7 more
wiley   +1 more source

Cranial nerves involvement in craniosynostosis: a systematic review. [PDF]

open access: yesChilds Nerv Syst
Manara R   +8 more
europepmc   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

open access: yesCell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu   +5 more
wiley   +1 more source

Fungal infection affects sexual signalling and mate choice in the sugarcane borer

open access: yesEcological Entomology, EarlyView.
Fungus‐infected Diatraea saccharalis females exhibit enhanced attractiveness to males in wind tunnel assays. Fungal infection alters the pheromone profile of females, increasing the relative abundance of Z9‐16: Ald, a minor but behaviourally active component of the species' sex pheromone blend.
Amanda C. Tuler   +3 more
wiley   +1 more source

Olfactory Groove Schwannoma: a rare case report. [PDF]

open access: yesDiscov Oncol
Tao Y   +5 more
europepmc   +1 more source

Imidacloprid Alters Activity and Responses to a Visual Predator Stimulus in Aussie Bronze Jumping Spiders (Helpis minitabunda, Araneae, Salticidae)

open access: yesEthology, EarlyView.
A field‐recommended concentration of a commercial imidacloprid formulation reduced open arena activity and slowed climbing in the jumping spider Helpis minitabunda. Exposed spiders still detected a looming predator stimulus, but their responses were reduced.
Reshnu Rajan‐Sheela   +2 more
wiley   +1 more source

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