Results 71 to 80 of about 15,434 (210)

Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system [PDF]

, 2015
Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on
Bell, Diana, Hanna, Ehab Y., Saade, Rami E.   +2 more
core  

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, Volume 41, Issue 2, Page 297-314, February 2026.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Mouse neuroblastoma cell-based model and the effect of epileptic events on calcium oscillations and neural spikes [PDF]

, 2013
Recently, mouse neuroblastoma cells have been considered as an attractive model for the study of human neurological and prion diseases, and they have been intensively used as a model system in different areas. For example, the differentiation of neuro2a (
Baek, Juyoung, Jung, Unsang, Jung, Woonggyu, Kang, Shinwon, Kim, Jeehyun, Kim, Suhwan, Lee, Sangwon   +6 more
core   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, Volume 158, Issue 2, Page 357-367, 15 January 2026.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Olfactory neuroblastoma: a rare sinonasal malignancy

Journal of the Pakistan Medical Association
Olfactory neuroblastoma is a rare malignant tumour arising from the olfactory nerve and extending into the nasal cavity. In this case report, the case of a 42-year-old male is presented.
Athar Adnan Uppal, Saira Zaman, Ayesha Shahbaz, Sadia Iram   +3 more
doaj   +1 more source

Advances in Stem Cells Biology: New Approaches to Understand Depression [PDF]

, 2016
Depression is a highly prevalent complex neuropsychiatric disorder, which ranks first of all mental and neurological disorders as contributor to the global burden of disease. However, available treatments are still far from ideal as for their specificity
A. Borsini, P. A. Zunszain
core   +3 more sources

Initial follow‐up of mechanical QC tests for RapidArc Dynamic (RAD)

Journal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background RapidArc Dynamic (RAD) is a new solution for delivery of radiotherapy introduced by Varian. RAD blends Volumetric Modulated Arc Therapy (VMAT) and Intensity‐Modulated Radiation Therapy (IMRT) by pausing gantry rotation at predefined positions and adds a degree of freedom: a dynamic collimator.
Emma Van Riet, Wout Piot, Bianca Vanstraelen, Karel Aerts, Truus Reynders, Tom Depuydt, Wouter Crijns   +6 more
wiley   +1 more source

A  Rare  Case of Sinonasal Carcinoma-Olfactory Neuroblastoma

Bengal Journal of Otolaryngology and Head Neck Surgery
INTRODUCTION Over the past decade, the pathology of un differentiated sinonasal malignancies has undergone extensive study, leading to significant advancements in the depiction and histopathological classification of various entities.
Vishal Magdum, Aishwarya A Kachare, Rahul Gosavi, Manali Joshi   +3 more
doaj   +1 more source

Neoadjuvant chemotherapy in the setting of locally advanced olfactory neuroblastoma with intracranial extension

Rare Tumors, 2011
Olfactory neuroblastoma (esthesioneuro­blastoma) is a rare malignant tumor of neuroectodermal origin. With only about 1,000 cases reported, there are no clear guidelines regarding management of this disease. Intracranial extension and orbital involvement
Raid Aljumaily, John S. Nystrom, Richard O. Wein   +2 more
doaj   +1 more source