Results 71 to 80 of about 7,995 (197)
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs +4 more
wiley +1 more source
Retropharyngeal Lymph Node Metastasis from Olfactory Neuroblastoma : A Report of 2 Cases [PDF]
Olfactory neuroblastoma is a rare, malignant neoplasm arising from the olfactory epithelium. It has an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis.
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Neuroblastoma is rare in the adult population, especially in thoracic or mediastinal locations, with only 25 previously reported cases. We report an additional example of primary thymic neuroblastoma in a previously asymptomatic 71-year-old man with an ...
Katrina Collins +2 more
doaj +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
Olfactory Neuroblastoma in Children: Results of Multimodality Treatment in 2 Patients
Olfactory neuroblastoma, a rare malignancy of the olfactory epithelium, is an uncommon tumor in children. It occurs mostly in older individuals and the treatment strategies are based on the experience with adults. In this report, clinical characteristics
Buyukpamukcu, Muenevver +5 more
core +1 more source
A Rare Case of Sinonasal Carcinoma-Olfactory Neuroblastoma
INTRODUCTION Over the past decade, the pathology of un differentiated sinonasal malignancies has undergone extensive study, leading to significant advancements in the depiction and histopathological classification of various entities.
Vishal Magdum +3 more
doaj +1 more source
Microplastics as a Silent Threat to Child Neurodevelopment: Evidence and Perspectives on Autism
Microplastics and nanoplastics can likely cross various biological barriers and promote the development of oxidative stress and neuroinflammation, and they can also interfere with crucial events during brain development. Although none of these effects are causally linked to autism spectrum disorders, the microparticles and nanoparticles are the first ...
David Santos Grillo +5 more
wiley +1 more source
Olfactory neuroblastoma (esthesioneuroblastoma) is a rare malignant tumor of neuroectodermal origin. With only about 1,000 cases reported, there are no clear guidelines regarding management of this disease. Intracranial extension and orbital involvement
Raid Aljumaily +2 more
doaj +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Cloutier, J-F +4 more
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