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Olfactory pathways and the sense of smell

Neuroscience & Biobehavioral Reviews, 1992
Rats were trained using operant conditioning to detect isoamyl acetate vapor generated by an olfactometer. They received lesions of olfactory pathways and were tested for retention of the odor detection task and trained on two-odor tasks. Deficits in odor detection and two-odor discrimination were related to the extent to which lesions disconnected the
B M, Slotnick, F W, Schoonover
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Repair of neural pathways by olfactory ensheathing cells

Nature Reviews Neuroscience, 2007
Damage to nerve fibre pathways results in a devastating loss of function, due to the disconnection of nerve fibres from their targets. However, some recovery does occur and this has been correlated with the formation of new (albeit abnormal) connections.
Geoffrey, Raisman, Ying, Li
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Olfactory Marker Protein in the Human Olfactory Pathway

Archives of Otolaryngology - Head and Neck Surgery, 1985
The presence of olfactory marker protein (OMP) in the olfactory tissue of rats, gerbils, and humans was demonstrated with goat antiserum to rat OMP. In control studies on rat neural tissue, OMP was found to be located in the olfactory receptor cells, nerves, and bulbs. Likewise, staining of OMP was found in the olfactory tissues of gerbils.
T, Nakashima, C P, Kimmelman, J B, Snow
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The Extrabulbar Olfactory Pathway: Primary Olfactory Fibers Bypassing the Olfactory Bulb in Bony Fishes?

Brain, Behavior and Evolution, 1995
Recent evidence has revealed that some primary olfactory fibers bypass the olfactory bulb and terminate in tel- and/or diencephalic areas (extrabulbar olfactory pathway, EBOP). We investigated the projections of this system in different fishes by means of soybean agglutinin binding studies. In all species in which primary olfactory fibers were labelled,
M H, Hofmann, D L, Meyer
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Carnosine in the Primary Olfactory Pathway

Science, 1974
Carnosine (β-alanyl-L-histidine) is present in mouse olfactory bulbs and nasal olfactory epithelium at concentrations exceeding that previously reported for any brain region of any species. After peripheral deafferentation, carnosine concentrations in the olfactory bulbs decrease to less than 10 percent that of normal, while other amino compounds are ...
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Changes in Peripheral Olfactory Pathways in Rheumatoid Arthritis

Journal of Computer Assisted Tomography, 2021
Objectives We investigated olfactory bulb (OB) volumes and olfactory sulcus (OS) depths in patients with rheumatoid arthritis (RA). Methods In this retrospective study, cranial magnetic resonance images of 68 adult patients were included.
Kultur, Turgut   +4 more
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Neurotrophic factors in the primary olfactory pathway

Progress in Neurobiology, 2000
The number of identified growth factors continues to increase rapidly with many being implicated in the development of the nervous system, although for most of them the autocrine and paracrine pathways of cellular regulation still remain to be elucidated.
A, Mackay-Sima, M I, Chuahb
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Olfactory learning induces differential long-lasting changes in rat central olfactory pathways

Neuroscience, 2001
In the present work, we investigated lasting changes induced by olfactory learning at different levels of the olfactory pathways. For this, evoked field potentials induced by electrical stimulation of the olfactory bulb were recorded simultaneously in the anterior piriform cortex, the posterior piriform cortex, the lateral entorhinal cortex and the ...
Fort, A.   +8 more
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Molecular Development of the Olfactory Nerve Pathway

Annals of the New York Academy of Sciences, 1998
ABSTRACT: There are, at least, two major questions concerning the molecular development of the olfactory nerve pathway. First, what are the molecular cues responsible for guiding axons from the nasal cavity to the olfactory bulb? Second, what is the molecular basis of axon targeting to specific glomeruli once axons reach the olfactory bulb?
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