Results 181 to 190 of about 61,010 (257)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Effects of Mechanical Nasal Stimulation on Olfaction. [PDF]

Med Devices (Auckl)
Bartley J, Garbelli L, Amjad I, White DE.   +3 more
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Impacts of different treatment methods on patients with COVID-related olfactory dysfunction: a systematic review and network meta-analysis. [PDF]

Clinics (Sao Paulo)
You W, Luo L, Zhou P, He T, Shao M, Jiao T, An X.   +6 more
europepmc   +1 more source

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source

The olfactory-glymphatic syndrome: linking smell dysfunction, cognitive impairment and sleep disturbances in neuropathological disorders. [PDF]

Front Neurosci
Phillips WT, Schwartz JG.
europepmc   +1 more source

The Incidence of Sensorineural Hearing Loss Diagnoses in People with and without Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and sensorineural hearing loss (SNHL) are both prevalent conditions among older adults. Although increasing number of studies have investigated SNHL as a risk factor for PD, it is not well known how diagnosed PD affects the likelihood of SNHL diagnosis.
Kaisa Hokkinen, Aarno Dietz, Pasi Lampela, Sirpa Hartikainen, Anna‐Maija Tolppanen   +4 more
wiley   +1 more source

Exploring the Paradoxical Association Between Chest CT Pulmonary Involvement and Olfactory Dysfunction in COVID-19 Patients: A Prospective Cross-Sectional Study. [PDF]

Health Sci Rep
Ghadimi-Moghadam A, Askari S, Ghatee MA, Mortazavi A, Javdansirat S, Moghadam AG, Vafapour H, Salehi Z, Mortazavi SMJ, Sihver L.   +9 more
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Does Xylitol Have Additional Benefit Over Saline for Nasal Irrigation in Chronic Rhinosinusitis?

The Laryngoscope, EarlyView.
Shahid Iqbal, Adam DeConde, Deborah Watson   +2 more
wiley   +1 more source