Results 101 to 110 of about 536,462 (222)

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

open access: yesMovement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju   +7 more
wiley   +1 more source

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

open access: yesMovement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans   +4 more
wiley   +1 more source

Olfactory tract

open access: yes, 1997
Olfactory tract.

core  

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron   +5 more
wiley   +1 more source

The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski   +7 more
wiley   +1 more source

Lateral olfactory tract usher substance (LOTUS), an endogenous Nogo receptor antagonist, ameliorates disease progression in amyotrophic lateral sclerosis model mice. [PDF]

open access: yesCell Death Discov, 2023
Ikeda T   +14 more
europepmc   +1 more source

Connectivity, plasticity, and function of neuronal circuits in the zebrafish olfactory forebrain [PDF]

open access: yes, 2014
For most living animals such as worms, insects, fishes, rodents and humans, chemical cues from the environment (odorants) play critical roles in guiding behaviors important for survival, including preying, mating, breeding, and escaping.
Zou, Ming
core   +1 more source

Efficacy of Exhalation Delivery System With Fluticasone in Chronic Rhinosinusitis With Versus Without Polyps

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate whether treatment responses to the exhalation delivery system with fluticasone (EDS‐FLU; XHANCE®) differ between patients with CRS with nasal polyps (CRSwNP) and patients without nasal polyps (CRSsNP). Study Design Post hoc analysis of the ReOpen clinical trials conducted between November 2018 and November 2021 for a 24 ...
Rodney J. Schlosser   +12 more
wiley   +1 more source

Host location in a specialist parasitoid wasp via olfactory cues – a physiological, behavioural and morphological study

open access: yes, 2012
For successful host location, parasitoids are thought to have evolved different strategies to filter relevant olfactory cues which indicate the presence of the host. Because of their versatility in their ecology and behaviour, as well as their fine tuned
Groll, Helga
core   +1 more source

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