Results 211 to 220 of about 52,178 (292)

Early Skin‐To‐Skin Contact Enhanced Feeding Behaviours and Stabilised Thermal Transition in Neonates Born by Caesarean

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Early skin‐to‐skin contact (SSC) is recommended after vaginal birth, but its implementation and evidence for Caesarean delivery remain limited. This study aimed to evaluate the impact of early SSC on neonatal adaptation and feeding behaviours in infants born via Caesarean section.
Ting Chen   +6 more
wiley   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

open access: yesBrain Pathology, EarlyView.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong   +8 more
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda   +5 more
wiley   +1 more source

A Randomized Controlled Trial of the Effectiveness of Olfactory Training on Loss of Smell Related to COVID-19: Results of the SMELL Trial and Extension Study

open access: green
Nicolas De Cleene   +10 more
openalex   +1 more source

In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome   +6 more
wiley   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli   +8 more
wiley   +1 more source

A New Experimental Setup to Study the Olfactory Behaviour of Trichogramma Egg Parasitoids

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We developed an experimental setup to assess odor‐induced egg‐laying behavior in tiny egg‐parasitoid wasps. This Y‐shaped olfactometer, coupled with an AI‐based image‐recognition model, automatically quantifies egg parasitism by Trichogramma wasps. Olfactory‐driven egg‐laying preferences were analyzed using Bayesian inference.
Cécile Bresch, Louise van Oudenhove
wiley   +1 more source

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