<i>NEAT</i> and tidy: a novel RT-PCR method for the independent quantification of the <i>NEAT1_1</i> isoform. [PDF]
Smith NE, Petersen J, Michael MZ.
europepmc +1 more source
Structural variation drives rhizome innovation and adaptive divergence in sister Medicago species
Chromosome‐scale genome analysis, population resequencing, stress‐responsive transcriptomes and functional assays showed that coding and regulatory structural variants, especially gene duplications and noncoding presence‐absence variants, underlie rhizome formation in alpine Medicago archiducis‐nicolai and contrasting xeric adaptation in its non ...
Hongyin Hu +14 more
wiley +1 more source
Single cell transcriptional perturbome in pluripotent stem cell models. [PDF]
Balmas E +10 more
europepmc +1 more source
Analysis of a near‐complete assembly of the genome of the highly transformable maize inbred line LH244 revealed its high genetic similarity to B73 and will serve as a much‐needed resource for functional genomics and genome editing of maize. ABSTRACT The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and ...
Kaiwen Tan +14 more
wiley +1 more source
CountASAP: a lightweight, easy to use python package for processing ASAPseq data. [PDF]
Boughter CT +13 more
europepmc +1 more source
Transcriptional outputs and condensates – formation and function
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin +4 more
wiley +1 more source
Simultaneous capture of single cell RNA-seq, ATAC-seq, and CRISPR perturbation enables multiomic screens to identify gene regulatory relationships. [PDF]
Shevade K +13 more
europepmc +1 more source
Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr +8 more
wiley +1 more source
Current Status of Multimodal Therapy for Oligometastatic Disease, Induced Oligometastatic Disease, and Oligo-Progressive Disease in <i>EGFR</i>-Mutated Non-Small-Cell Lung Cancer. [PDF]
Miyawaki T +6 more
europepmc +1 more source
Small heat shock protein HSPB5 uses disorder to bind zinc with high affinity. [PDF]
Janowska MK +4 more
europepmc +1 more source

