Results 121 to 130 of about 68,127 (203)

Enzymatic Encoding of Topology in an Intrinsically Disordered Single‐Chain Protein

Angewandte Chemie, EarlyView.
Enzymatic intramolecular cross‐linking enables topology control in intrinsically disordered proteins, yielding SCNPs with reproducible cavity architectures. Using β‐casein and microbial transglutaminase, sparse, sequence‐resolved constraints drive compact collapse without inducing secondary structure.
Joshua Johani, Kristin Eichelberger, Olga Guskova, Simbulele Charlotte Dunjwa, Hans Bolinsson, Anna‐Maria Börjesdotter, Lars Nilsson, Doris Jaros, Harald Rohm, Albena Lederer   +9 more
wiley   +2 more sources

Editorial: Beta-Amyloid oligomer specific treatments for Alzheimer's disease

Frontiers in Neuroscience, 2023
Heinz Hillen
doaj   +1 more source

Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach. [PDF]

Anal Chem
Svingou D, McAlary L, Harrison JA, Zenobi R.   +3 more
europepmc   +1 more source

Geometric Nonuniformity Localizes Valence Orbitals in Gold Clusters: Case Study on [Au23(SC6H11)16]–

Angewandte Chemie, EarlyView.
The electronic structure of [Au23(SC6H11)16]–, a monolayer‐protected gold cluster with a nonuniform Au13 core, was investigated. Anion photoelectron spectroscopy and density functional theory calculations revealed that the highest occupied molecular orbital (HOMO) and HOMO‐1 are localized on the two triangular Au3 units at the ends of the Au13 core ...
Yosuke Asami, Shun Ito, Kiichirou Koyasu, Tatsuya Tsukuda   +3 more
wiley   +2 more sources

Immunotolerant Oligomer scaffolds promote regenerative remodeling and improved muscle structure and function after volumetric muscle loss. [PDF]

Sci Rep
Morrison RA, Sexton J, Zhang L, Dong E, Phillips M, Gao H, Liu Y, Qazi TH, Halum S, Voytik-Harbin SL.   +9 more
europepmc   +1 more source

Light and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems

Angewandte Chemie, EarlyView.
Here, we report a photoswitchable synthetic peptide that, under light energy cycles, exhibits supramolecular polymorphism coupled to darkness‐driven structural self‐selection. We demonstrate that light sustains a transient assembled state in the form of helical nanoribbons, hindering the system from undergoing a transition to the disassembled state ...
Alejandro Méndez‐Ardoy, Nicolas Cissé, Adrian Sanchez‐Fernandez, Patricia Fulias‐Guzmán, Marc C. A. Stuart, Tibor Kudernac, Javier Montenegro   +6 more
wiley   +2 more sources

Oligomer logic of memory molecules. [PDF]

Mol Brain
Rudy JW.
europepmc   +1 more source

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

Angewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans, Nishu Yadav, Wouter A. Remmerswaal, Daan Hoogers, Koen N. A. van de Vrande, Sarah Hosking, Ana Poveda, Jeroen D. C. Codée, Jesús Jiménez‐Barbero, Martina Delbianco, Gavin J. Miller   +10 more
wiley   +2 more sources

Topology-controlled dynamic conjugated oligomers from tetra-arylsubstituted alkene building blocks. [PDF]

Nat Commun
Bian Q, Zhao Y, Zhang C, Zhang Y, Zhang Y, Zeng Z, Tang BZ, Xie S.   +7 more
europepmc   +1 more source

Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation

Angewandte Chemie, EarlyView.
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen, Andreas Møllebjerg, Samuel Peña‐Díaz, Rosie Graham, Nicolai Claus Petersen, Bjørk Nolsøe Isaksen, Mathias Carstensen, Martin B. Johansen, Andreas Sommerfeldt, Allan R. Petersen, Iddi Khamisi Chuma, Cecilie Ryberg, Thomas Rea Wittenborn, Virginia Gichuru, Huabing Wang, Carsten Scavenius, Alexander Sandahl, Daniel E. Otzen   +17 more
wiley   +2 more sources