Results 121 to 130 of about 26,087 (219)

Resolving oligomeric states of photoactivatable proteins in living cells via photon counting histogram analysis. [PDF]

iScience
Camp T, Li Z, Li Y, Oh TJ, Zhang K.
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Generation and Characterization of HDV-Specific Antisera with Respect to Their Application as Specific and Sensitive Research and Diagnostic Tools. [PDF]

Viruses
Thiyagarajah K, Hein S, Raupach J, Adeel N, Miller J, Knapp M, Welsch C, Glitscher M, Görgülü E, Stoffers P, Lembeck P, Trebicka J, Ciesek S, Peiffer KH, Hildt E.   +14 more
europepmc   +1 more source

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

Advanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi, Brooke E. Silverstein, Yulia Shmidov, Sonal Deshpande, Joy Tong, Yvonne Y. Ma, Chinmay S. Potnis, Soumen Saha, Xinghai Li, Max R. Ney, Sarah Y. Kim, Joshua J. Milligan, Lixin Fan, Matthew L. Becker, Daniel Reker, Ashutosh Chilkoti   +15 more
wiley   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

Bridging PCR-Based Genome-Walking Protocol. [PDF]

Bio Protoc
Li M, Gu Y, Tang Q, Li H.
europepmc   +1 more source

DLP 4D Printing of Programmable Molecularly‐Engineered Liquid Crystal Elastomer Actuators

Advanced Science, EarlyView.
We introduce an original and versatile approach for printing liquid crystal elastomers that exhibit reversible shape morphing using digital light processing. 3D‐tructures are printed in a partially cured state, mechanically programmed, and then fully crosslinked to fix molecular alignment.
Rakine Mouhoubi, Vincent Lapinte, Sébastien Blanquer   +2 more
wiley   +1 more source

Enhanced detection of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) antibodies in various animal species using oligomeric nucleocapsid protein-based diagnostics. [PDF]

Virol J
Chang YC, Shimoda H, Wen HW, Maeda K, Tseng CY, Tsai CH, Hsu WL.   +6 more
europepmc   +1 more source

A Mini‐Spidroin Forms High‐Performance Artificial Spider Silk via Edge‐Cysteine–Locked β‐Sheet Assembly

Advanced Science, EarlyView.
Cysteine‐engineered mini‐spidroins (∼33 kDa) undergo phosphate‐induced liquid–liquid phase separation (LLPS), where disulfide bonds lock partially aligned polyA segments. Subsequent microfluidic spinning promotes directional β‐sheet crystallization, producing fibers with 531 MPa strength and 182 MJ/m3 toughness.
Min Li, Huan Chen, Qi Zhang, Xiaoyun Xu, Yini Zheng, Chunyu Lyu, Weibin Jia, Jun Fan, Fu‐Rong Chen, Wei Liu, Jinlian Hu   +10 more
wiley   +1 more source

Organization of the AKR Qa region [PDF]

, 1989
Bevec, Dorian, Grosshaus, C., Messer, Gerald, Schmidt, Walter, Schwemmle, Sabine, Steinmetz, M., Weiss, Elisabeth H.   +6 more
core   +1 more source