Results 151 to 160 of about 25,062 (219)

How does protein aggregate structure affect mechanisms of disaggregation? [PDF]

Biochem Soc Trans
Yang Y, Rye HS.
europepmc   +1 more source

In Situ Polymerization Controlled Growth of Perovskite via Benzoic Acid Crosslinking Agent for Highly Efficient and Mechanically Robust Flexible Perovskite Solar Cell

Advanced Science, EarlyView.
This study proposes a novel strategy to improve the performance of perovskite solar cells through the incorporation of the crosslinking agent 4‐HBA into the perovskite layer. The multifunctional properties of 4‐HBA contribute to power conversion efficiencies of 24.76% for rigid devices and 22.73% for flexible devices, both exhibiting remarkable ...
Yankun Yang, Na Yang, Chenxi Zhang, Shiqi Li, Yang Hao, Qinjun Sun, Zhihui Chen, Shengzhong (Frank) Liu, Fei Guo, Jianfeng Lu, Yuying Hao   +10 more
wiley   +1 more source

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

Advanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay, Hadeeqa G. Raza, Richard G. Doveston, Aneika C. Leney   +3 more
wiley   +1 more source

A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily. [PDF]

Nat Commun
Parr RJ, Santin YG, Ratkevičiūte G, Caulton SG, Radford P, Gurvič D, Jenkins M, Doyle MT, Mead L, Silale A, van den Berg B, Knowles TJ, Sockett RE, Stansfeld PJ, Laloux G, Lovering AL.   +15 more
europepmc   +1 more source

Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43

Advanced Science, EarlyView.
Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang, Qi Wang, Ruolan Yan, Xiaochuan Wang, Jianlan Gu   +4 more
wiley   +1 more source

Sequencing and Optical Genome Mapping for the Adventurous Chemist. [PDF]

Chem Biomed Imaging
Ruppeka Rupeika E, D'Huys L, Leen V, Hofkens J.   +3 more
europepmc   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Chemometric analysis of ethoxylated polymer products using extracted MALDI-TOF-MS peak distribution features. [PDF]

PLoS One
Dickinson E, Cawthorne RN, Dodds P, Atkinson GM, García Thomas PF, Jones L, Crosbie M, Cook J, Wilson J.   +8 more
europepmc   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Enhancing the Solid-State Emission of Carbonyl-Containing Compounds by Means of Introducing a Bifuran Core. [PDF]

ACS Appl Opt Mater
Yakir HR, Bogoslavsky B, Gidron O.
europepmc   +1 more source