A Phasin with Many Faces: Structural Insights on PhaP from Azotobacter sp. FA8 [PDF]
, 2014 Phasins are a group of proteins associated to granules of polyhydroxyalkanoates (PHAs). Apart from their structural role as part of the PHA granule cover, different structural and regulatory functions have been found associated to many of them, and ...
Bucci, Hernán Andrés +5 more
core +4 more sources
A high throughput molecular force assay for protein-DNA interactions. [PDF]
, 2011 An accurate and genome-wide characterization of protein–DNA interactions such as transcription factor binding is of utmost importance for modern biology. Powerful screening methods emerged.
Albrecht +42 more
core +1 more source
The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]
, 1992 An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas +4 more
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Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant - Implications for disease susceptibility to Creutzfeldt-Jakob disease [PDF]
, 2004 The human PrP gene (PRNP) has two common alleles that encode either methionine or valine at codon 129. This polymorphism modulates disease susceptibility and phenotype of human transmissible spongiform encyphalopathies, but the molecular mechanism by ...
Abdessamad Tahiri-Alaoui +56 more
core +1 more source
Domain interactions within Fzo1 oligomers are essential for mitochondrial fusion [PDF]
, 2006 Mitofusins are conserved GTPases essential for the fusion of mitochondria. These mitochondrial outer membrane proteins contain a GTPase domain and two or three regions with hydrophobic heptad repeats, but little is known about how these domains interact ...
Chan, David C., Griffin, Erik E.
core +3 more sources
GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET [PDF]
, 2009 The mouse γ-aminobutyric acid (GABA) transporter mGAT1 was expressed in neuroblastoma 2a cells. 19 mGAT1 designs incorporating fluorescent proteins were functionally characterized by [^3H]GABA uptake in assays that responded to several experimental ...
Abramoff +105 more
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Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release [PDF]
, 2020 Release of neurotransmitters relies on submillisecond coupling of synaptic vesicle fusion to the triggering signal: AP-evoked presynaptic Ca2+ influx.
Bello, Oscar D. +9 more
core +3 more sources
Safety assessment of the substance (butadiene, styrene, methyl methacrylate, butyl acrylate) copolymer cross-linked with divinylbenzene or 1,3-butanediol dimethacrylate for use in food contact materials [PDF]
, 2016 Publisher ...
Andrew Smith +24 more
core +1 more source
Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype [PDF]
, 2015 Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses.
Citron, Michael +6 more
core +4 more sources
, 2009 The energetic optimization problem, e.g., searching for the optimal switch- ing protocol of certain system parameters to minimize the input work, has been extensively studied by stochastic thermodynamics.
Gong, Linchen +2 more
core +1 more source