Results 131 to 140 of about 641,320 (378)

Targeting of the Transcription Factor STAT4 by Antisense Phosphorothioate Oligonucleotides Suppresses Collagen-Induced Arthritis [PDF]

, 2007
Kai Hildner, Peter Schirmacher, Imke Atreya, Maria Dittmayer, Brigitte Bartsch, Peter R. Galle, Stefan Wirtz, Markus F. Neurath   +7 more
openalex   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

A postsynthetically 2’-“clickable” uridine with arabino configuration and its application for fluorescent labeling and imaging of DNA

Beilstein Journal of Organic Chemistry, 2017
The arabino-configured analog of uridine with a propargyl group at the 2’-position was synthesized and incorporated into DNA by solid-phase chemistry. The fluorescence quantum yields of DNA strands that were postsynthetically modified by blue and green ...
Heidi-Kristin Walter, Bettina Olshausen, Ute Schepers, Hans-Achim Wagenknecht   +3 more
doaj   +1 more source

Kinetic Hairpin Oligonucleotide Blockers for Selective Amplification of Rare Mutations [PDF]

, 2014
Yanwei Jia, J. Aquiles Sanchez, Lawrence J. Wangh   +2 more
openalex   +1 more source

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid‐Responsive Ketal Side Groups

Advanced Materials, EarlyView.
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck, Michael Fichter, Laura J. Rosenberger, Jannis Willig, Alexander Fuchs, Felicia Schön, Paul Schneider, Carolina Medina‐Montano, Taufiq Ahmad, Jessica Erlenbusch, Pol Besenius, Leonard Kaps, Matthias Bros, Stephan Grabbe, Volker Mailänder, Jürgen Groll, Lutz Nuhn   +16 more
wiley   +1 more source

Single-Cell Enumeration of an Uncultivated TM7 Subgroup in the [PDF]

, 2003
Specific oligonucleotide hybridization conditions were established for single-cell enumeration of uncultivated TM7 and IO25 bacteria by using clones expressing heterologous 16S rRNA. In situ analysis of human subgingival crevice specimens revealed that a
Armitage, Gary C., Ouverney, Cleber C., Relman, David A.   +2 more
core   +1 more source

Decoupling Dynamics and Crosslink Stability in Supramolecular Hydrogels Using Associative Exchange

Advanced Materials, EarlyView.
How does reorganization impact the stability of supramolecular hydrogels? In contrast to dissociative crosslink exchange, implementing associative exchange in macroscale DNA hydrogels enables decoupling of reorganization dynamics from thermal and mechanical stability.
Pierre Le Bourdonnec, Charafeddine Ferkous, Léo Comunale, Luca Cipelletti, Rémi Merindol   +4 more
wiley   +1 more source

Discovery of tumoricidal DNA oligonucleotides by effect-directed in-vitro evolution [PDF]

, 2019
Noam Mamet, Yaniv Amir, Erez Lavi, Liron Bassali, Gil Harari, Itai Rusinek, Nir Skalka, Elinor Debby, Mor Greenberg, Adva Zamir, Anastasia Paz, Neria Reiss, Gil Loewenthal, Irit Avivi, Avichai Shimoni, Guy Neev, Almogit Abu-Horowitz, Ido Bachelet   +17 more
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Exploration, normalization, and summaries of high density oligonucleotide array probe level data.

Biostatistics, 2003
R. Irizarry, Bridget G. Hobbs, F. Collin, Y. Beazer-Barclay, Kristen J Antonellis, U. Scherf, T. Speed   +6 more
semanticscholar   +1 more source