Results 201 to 210 of about 413,466 (243)

OpenIDS2: A low-cost, 3D-printed, open-source platform for reproducible construction of DNA microarray synthesizers. [PDF]

PLoS One
Kim J, Kim H, Bang D.
europepmc   +1 more source

Therapeutic Efficacy and Safety Profile of Eplontersen in Hereditary Transthyretin-Mediated Amyloidosis: A Systematic Review. [PDF]

Health Sci Rep
Patel ZV, Kumari V, Paras, Deepak BL, Prajjwal P, Deep KN, Bai R, John SS, Hussin OA.   +8 more
europepmc   +1 more source

Deep-mutational scanning libraries using Tiled-Region Exchange mutagenesis. [PDF]

G3 (Bethesda)
Kindree K, Chochinov CA, Bhachu K, Cheng Y, Caron A, McDonald M, Mamai Z, Nguyen Ba AN.   +7 more
europepmc   +1 more source

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Antisense Oligonucleotides

Nephron Experimental Nephrology, 1998
Antisense technology was developed to inhibit gene expression by utilizing an oligonucleotide complementary to the mRNA which encodes the target gene. There are a few possible mechanisms for the inhibitory effects of antisense oligonucleotides. Among them, degradation of mRNA by RNase H is considered to be the major mechanism of action for antisense ...
N, Kashihara, Y, Maeshima, H, Makino
openaire   +2 more sources

Oligonucleotidic therapeutics

Expert Opinion on Drug Discovery, 2008
Numerous oligonucleotide-based biopharmaceuticals have been tested to suppress disease progression. These potent therapeutics include plasmids containing transgenes, antisense oligonucleotides, ribozymes, DNAzymes, decoys, aptamers and small interfering RNAs.
Yoshitaka, Isaka, Enyu, Imai, Shiro, Takahara, Hiromi, Rakugi   +3 more
openaire   +2 more sources