Results 231 to 240 of about 635,743 (331)

Unlocking atom-specific radiotherapy - DNA backbone breakage caused by X-ray photoactivation. [PDF]

Chem Sci
Svensson PHW, Rydgren B, Schwob L, Berholts M, Stenerlöw B, Hocine Hafiani O, André T, Grånäs O, Timneanu N, Leroux J, Nair A, Pille L, Oostenrijk B, Bari S, Björneholm O, Caleman C.   +15 more
europepmc   +1 more source

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

Advanced Science, EarlyView.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing, Yufan Qin, Zhijin Li, Xiufang Yu, Jianbo Wang, Xiaoqiong Liu, Xin Chen, Chao Yu   +7 more
wiley   +1 more source

Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity. [PDF]

Nucleic Acids Res
Gooran N, Borsa BA, Hernandez FJ, Härmä H, Kopra K.   +4 more
europepmc   +1 more source

High-density perfusion cultures of the marine bacterium Rhodovulum sulfidophilum for the biomanufacturing of oligonucleotides

Francesco Iannacci, João Medeiros Garcia Alcântara, Martina Marani, Paolo Camesasca, Michele Chen, Fani Sousa, Massimo Morbidelli, Mattia Sponchioni   +7 more
openalex   +1 more source

Oligonucleotides Produced by Digestion of Bakers' Yeast Serine Transfer Ribonucleic Acid with Specific Nucleases

, 1967
Francis A. Neelon, Mario Molinaro, Hisayuki Ishikura, Lewis B. Sheiner, Giulio L. Cantoni   +4 more
openalex   +1 more source

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

Advanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li, Ruixue Ai, Xinjiani Chen, Yaning Wang, Chenlei Pan, Suxian Song, Chenjie Yang, Yu Zhou, Zhen Zhang, Xiaojun Liu, Xiaodi Liu, Liping Yao, Quanbao Zhang, Wenxue Gu, Rongqing Zhang   +14 more
wiley   +1 more source

ASOG: AntiSense Oligonucleotide Generator. [PDF]

Comput Struct Biotechnol J
Kimi J, Korczak P, Vialet B, Roubin E, Barthélémy P, Campagne S, Malard F.   +6 more
europepmc   +1 more source

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

Advanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee, Minjae Kim, Gha Yeon Park, Jubeen Yoon, Kunyoo Shin, Chang Ho Sohn, Myunghwan Choi   +6 more
wiley   +1 more source

Application of Antisense Oligonucleotides as an Alternative Approach for Gene Expression Control and Functional Studies. [PDF]

Int J Mol Sci
Szukowska A, Żuk M, Sztompke J, Bednarz B, Kaźmierczak U.   +4 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source