Results 231 to 240 of about 631,547 (339)

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang, Yu Du, Pengkun Xu, Luyu Zhong, Zhi Li, Wenran Zhu, Yicheng Li, Bo Cheng, Xinyuan Chang, Yawei Fan, Yibo Li   +10 more
wiley   +1 more source

Multimodal glioma immunotherapy combining TLR9-targeted STAT3 antisense oligodeoxynucleotides with PD1 immune checkpoint blockade. [PDF]

Neuro Oncol
Hung CY, Kang EY, Jacek K, Yu C, Zhang X, Zhu Y, Aftabizadeh M, Wong RA, Badie B, Świderski P, Kamińska B, Alizadeh D, Heimberger AB, Brown CE, Kortylewski M.   +14 more
europepmc   +1 more source

Isolation and sequence determination of 5'-terminal oligonucleotide fragments of RNA transcripts synthesized by bacteriophage T3-induced RNA polymerase from T3 DNA. [PDF]

, 1980
Umadas Maitra, Warren R. Jelinek, Arturo Yudelevich, Hemanta K. Majumder, Anirban Guha   +4 more
openalex   +1 more source

Internal Phase Separation in Synthetic DNA Condensates

Advanced Science, EarlyView.
The modular, programmable system of DNA nanostructures developed provides programmatic control over multiphase condensate behavior, enabling mapping onto a predictive Flory‐Huggins model. This combined experimental and theoretical framework will help address open questions in condensate biophysics and facilitate the rational design of functional ...
Diana A. Tanase, Dino Osmanović, Roger Rubio‐Sánchez, Layla Malouf, Elisa Franco, Lorenzo Di Michele   +5 more
wiley   +1 more source

A sweet barrier to gene silencing: Glucose metabolism interferes with antisense oligonucleotide therapy. [PDF]

Mol Ther Nucleic Acids
Duan S, Zhang W, Cao H.
europepmc   +1 more source

Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2′-OMe RNA. [PDF]

, 1989
Silvia M.L. Barabino, Brian S. Sproat, Ursula Ryder, B J Blencowe, Angus I. Lamond   +4 more
openalex   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Thiol-mediated uptake of phosphorothioate liposomes, visualized with fluorescent flippers. [PDF]

Chem Sci
Bouffard J, Bayard F, Sakai N, Matile S.
europepmc   +1 more source

The Structure of Tobacco Rattle Virus Ribonucleic Acids: Comparison of Large Oligonucleotides Derived from the 3' Ends

, 1978
P. Gugerli, G. Darby, A. C. Minson
openalex   +1 more source

Use of oligonucleotide hybridization in the characterization of a beta zero-thalassemia gene (beta 37 TGG----TGA) in a Saudi Arabian family [published erratum appears in Blood 1986 Jul;68(1):323] [PDF]

, 1986
CD Boehm, CE Dowling, PG Waber, PJ Giardina, HH Jr Kazazian   +4 more
openalex   +1 more source