Results 251 to 260 of about 641,320 (378)

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

Advanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye, Xiaoli Zhang, Lingfeng Qiu, Jia Ji, Jueqing Gu, Hongyu Jia, Yingfeng Lu, Jiyang Chen, Zelu Meng, Jiangshan Lian, Hangping Yao, Xun Zeng, Yida Yang   +12 more
wiley   +1 more source

Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking

Advanced Science, EarlyView.
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo‐crosslinking approach is presented that prolongs the lifetime of different structures in coacervate‐based artificial cells while maintaining dynamic formation.
Madelief A. M. Verwiel, Alexander B. Cook, Yiǧitcan Sümbelli, Nadia A. Erkamp, Jan C. M. van Hest   +4 more
wiley   +1 more source

Identification of Nuclearity of Chromium Binary Adducts with DNA by Negative Ion Mass Spectrometry: Short Communication. [PDF]

Biol Trace Elem Res
Kovitch K, Liang Q, Repke K, Atkinson EK, Woski SA, Vincent JB.   +5 more
europepmc   +1 more source

Secondary structure of the segment 5 genomic RNA of influenza A virus and its application for designing antisense oligonucleotides [PDF]

, 2019
Paula Michalak, Marta Soszynska-Jozwiak, Ewa Biała, Walter N. Moss, Julita Kęsy, Barbara Szutkowska, Elżbieta Lenartowicz, Ryszard Kierzek, Elżbieta Kierzek   +8 more
openalex   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer.

Experimental and molecular pathology (Print), 2009
P. Bates, D. Laber, Donald M Miller, S. Thomas, J. Trent   +4 more
semanticscholar   +1 more source

OpenIDS2: A low-cost, 3D-printed, open-source platform for reproducible construction of DNA microarray synthesizers. [PDF]

PLoS One
Kim J, Kim H, Bang D.
europepmc   +1 more source

Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics

, 2014
Axel Vater, Sven Klußmann
openalex   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

Advanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning, Munir H. Buhaya, Victor V. Nguyen, Afeefah Khazi‐Syed, Haider A. Ali, Adil Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, Victor D. Varner, Cheryl M. Lewis, Emina H. Huang, Jacopo Ferruzzi   +18 more
wiley   +1 more source

Oligonucleotide-stabilized Ag nanocluster fluorophores.

Journal of the American Chemical Society, 2008
Chris I. Richards, Sungmoon Choi, J. Hsiang, Y. Antoku, T. Vosch, A. Bongiorno, Yih-Ling Tzeng, R. Dickson   +7 more
semanticscholar   +1 more source